Results 121 to 130 of about 1,393,823 (260)

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

The effects of fluctuating temperatures on degree-day development and life history parameters of <i>Pseudacysta perseae</i> (Hemiptera: Tingidae). [PDF]

Ann Entomol Soc Am
Dadlani LP, Milosavljević I, Hoddle MS.
europepmc   +1 more source

Improving the degree-day model for forecasting Locusta migratoria manilensis (Meyen) (Orthoptera: Acridoidea). [PDF]

PLoS One, 2014
Tu X, Li Z, Wang J, Huang X, Yang J, Fan C, Wu H, Wang Q, Zhang Z.   +8 more
europepmc   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Assessment of planting soil temperature and growing degree day impacts on silage corn (Zea mays L.) biomass. [PDF]

J Anim Sci Technol
Kim M, Kim J, Jo MH, Sung K, Han KJ.
europepmc   +1 more source

Estimating West Nile virus transmission period in Pennsylvania using an optimized degree-day model. [PDF]

Vector Borne Zoonotic Dis, 2013
Chen S, Blanford JI, Fleischer SJ, Hutchinson M, Saunders MC, Thomas MB.   +5 more
europepmc   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Biology, temperature thresholds, and degree-day requirements for development of the cucumber moth, Diaphania indica, under laboratory conditions. [PDF]

J Insect Sci, 2014
Hosseinzade S, Izadi H, Namvar P, Samih MA.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

On accumulated degree day and maggot age calculations in Rivers and Dahlem (2023) The Science of Forensic Entomology, 2nd edition. [PDF]

J Med Entomol
Wells JD.
europepmc   +1 more source