Results 101 to 110 of about 7,058,514 (292)

John Robert Silber Honorary Degree Citation

open access: yes, 1970
1 p.Scholar and educator John Robert Silber received an honorary Doctor of Humane Letters degree at Scholars Day Convocation in 1970.

core   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

Rene Jules Dubos Honarary Degree Citation

open access: yes, 1971
1 p.Research scientist, environmentalist, and philosopher Rene Jules Dubos received an honorary Doctor of Humane Letters degree at Scholars Day Convocation in 1971.

core   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

open access: yesMolecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura   +19 more
wiley   +1 more source

Day-Degree Methods for Pest Management [PDF]

open access: yes, 1983
Recommendations are made for reporting day-degree methods which may have practical applications. Standardized thresholds (40, 50, and 60°F, or 5, 10, and 15°C) should be used.
Pruess, Kenneth P.
core  

Amory Bloch Lovins Honorary Degree Citation

open access: yes, 1983
1 p.Physicist, social scientist, and public policy advocate Amory Bloch Lovins received an honorary Doctor of Science degree at Scholars Day Convocation in 1983.

core   +1 more source

Local sensitivity analysis of heating degree day and cooling degree day temperature derivative prices

open access: yesQuantitative Finance
We study the local sensitivity of heating degree day (HDD) and cooling degree day (CDD) temperature futures and option prices with respect to perturbations in the deseasonalized temperature or in one of its derivatives up to a certain order determined by the continuous-time autoregressive process modelling the deseasonalized temperature in the HDD and ...
openaire   +3 more sources

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

open access: yesMolecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis   +3 more
wiley   +1 more source

Nancy L. Rosenblum Honorary Degree Citation

open access: yes, 1993
1 p.Professor of political science Nancy L. Rosenblum received an honorary Doctor of Humane Letters degree at Scholars Day Convocation in 1993.

core   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

open access: yesMolecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober   +16 more
wiley   +1 more source

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