Results 31 to 40 of about 41,896 (267)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Bijective Enumeration of Bicolored Maps of Given Vertex Degree Distribution [PDF]

open access: yesDiscrete Mathematics & Theoretical Computer Science, 2009
We derive a new formula for the number of factorizations of a full cycle into an ordered product of two permutations of given cycle types. For the first time, a purely combinatorial argument involving a bijective description of bicolored maps of ...
Alejandro Morales, Ekaterina Vassilieva
doaj   +1 more source

Four-vertex degree graphs of nonsolvable groups

open access: yesJournal of Algebra, 2013
For a finite group G, the character degree graph Δ(G) is the graph whose vertices are the primes dividing the degrees of the ordinary irreducible characters of G, with distinct primes p and q joined by an edge if pq divides some character degree of G. We determine all graphs with four vertices that occur as Δ(G) for some nonsolvable group G. Along with
Lewis, Mark L., White, Donald L.
openaire   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

Computation of Vertex Degree-Based Molecular Descriptors of Hydrocarbon Structure

open access: yesJournal of Chemistry, 2022
Topological indices are such numbers or set of numbers that describe topology of structures. Nearly 400 topological indices are calculated so far. The prognostication of physical, chemical, and biological attributes of organic compounds is an important ...
Zeeshan Saleem Mufti   +5 more
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

open access: yesMolecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto   +13 more
wiley   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

open access: yesFEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava   +3 more
wiley   +1 more source

Comparing degree–based energies of trees [PDF]

open access: yesContributions to Mathematics, 2021
Ivan Gutman
doaj   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

open access: yesFEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li   +8 more
wiley   +1 more source

The Vertex Degree Distance of One Vertex Union of Two Cycles

open access: yesJournal of Physics: Conference Series, 2019
Abstract One vertex union of two cycles is a kind of multi-cycle graphs. In this paper, the vertex degree distances of one vertex union of two cycles are calculated, and on this basis, the maximum and minimum of vertex degree distances are studied.
openaire   +1 more source

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