Results 71 to 80 of about 3,049,614 (273)
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Functional conservation of sequence determinants at rapidly evolving regulatory regions across mammals. [PDF]
Recent advances in epigenomics have made it possible to map genome-wide regulatory regions using empirical methods. Subsequent comparative epigenomic studies have revealed that regulatory regions diverge rapidly between genome of different species, and ...
Iksoo Huh +3 more
doaj +1 more source
Largest Laplacian Eigenvalue and Degree Sequences of Trees [PDF]
We investigate the structure of trees that have greatest maximum eigenvalue among all trees with a given degree sequence. We show that in such an extremal tree the degree sequence is non-increasing with respect to an ordering of the vertices that is ...
Biyikoglu, Tuerker +2 more
core +1 more source
Minimum-Loop Realization of Degree Sequences
Given a finite sequence D of nonnegative integers, let M(D) denote its maximum element and S(D) its sum. It is known that D is realizable as a degree sequence by some graph if and only if S(D) is even, and by a loopless graph if and only if the even integer S(D) - 2M(D) ⩾ 0.
Goldman, A. J., Byrd, R. H.
openaire +2 more sources
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Extremal Topological Indices with Prescribed Degree Sequences
This paper explores the extremal properties and bounds of two significant topological indices in graph theory: the Albertson and Sigma indices, with an emphasis on trees and bipartite graphs.
Hamoud, J., Belov, A.Ya.
doaj +1 more source
New Bounds For Degree Sequence Of Graphs [PDF]
Let $G = (V, E)$ be a simple graph with $n$ vertices, $m$ edges, and vertex degrees $d_1, d_2, ..., d_n$. Let $d_1, d_n$ be the maximum and and minimum degree of vertices. In this paper, we present lower and upper bounds for $\sum_{i=1}^{n}d_i^{2}$ and
Akbar Jahanbani
doaj
A permutation method for network assembly.
We present a method for assembling directed networks given a prescribed bi-degree (in- and out-degree) sequence. This method utilises permutations of initial adjacency matrix assemblies that conform to the prescribed in-degree sequence, yet violate the ...
Shawn A Means +2 more
doaj +1 more source
Reduced criteria for degree sequences
For many types of graphs, criteria have been discovered that give necessary and sufficient conditions for an integer sequence to be the degree sequence of such a graph. These criteria tend to take the form of a set of inequalities, and in the case of the Erd s-Gallai criterion (for simple undirected graphs) and the Gale-Ryser criterion (for bipartite ...
openaire +2 more sources
By dawn or dusk—how circadian timing rewrites bacterial infection outcomes
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo +2 more
wiley +1 more source

