Results 81 to 90 of about 5,199,165 (252)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

Cover time of a random graph with given degree sequence

open access: yes, 2012
In this paper we establish the cover time of a random graph G(d) chosen uniformly at random from the set of graphs with vertex set [n] and degree sequence d.
Cooper, Colin   +5 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

Flooding in dynamic graphs with arbitrary degree sequence

open access: yes, 2014
International audienceThis paper addresses the flooding problem in dynamic graphs, where flooding is the basic mechanism in which every node becoming aware of a piece of information at step tt forwards this information to all its neighbors at all ...
Fraigniaud, Pierre   +2 more
core   +1 more source

Hamiltonian-connected graphs and their strong closures

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1997
Let G be a simple graph of order at least three. We show that G is Hamiltonian-connected if and only if its strong closure is Hamiltonian-connected. We also give an efficient algorithm to compute the strong closure of G.
Pak-Ken Wong
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

The Neighbor Matrix: generalizing the degree sequence [PDF]

open access: yes, 2015
The newly introduced neighborhood matrix extends the power of adjacency and distance matrices to describe the topology of graphs. The adjacency matrix enumerates which pairs of vertices share an edge and it may be summarized by the degree sequence, a ...
Gera, Ralucca M.   +2 more
core   +1 more source

Degree-based connected graph construction with assortativity constraint

open access: yesNew Journal of Physics
Degree-based graph construction is a fundamental problem in network science. A graph is simple if there are no self-loops and no multiple links between any pair of nodes in the graph. A degree sequence $d = (d_1, d_2,\cdots, d_{N})$ is graphical if d can
Yingyue Ke, Piet Van Mieghem
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

open access: yesFEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source

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