Results 81 to 90 of about 3,049,614 (273)
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
A Tur\'an-type problem on degree sequence [PDF]
, 2013 Given $p\geq 0$ and a graph $G$ whose degree sequence is $d_1,d_2,\ldots,d_n$, let $e_p(G)=\sum_{i=1}^n d_i^p$. Caro and Yuster introduced a Tur\'an-type problem for $e_p(G)$: given $p\geq 0$, how large can $e_p(G)$ be if $G$ has no subgraph of a ...
Li, Xueliang, Shi, Yongtang
core
Molecular bases of circadian magnesium rhythms across eukaryotes
FEBS Letters, EarlyView.Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10
FEBS Letters, EarlyView.Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang +8 more
wiley +1 more source
On factorable degree sequences
Journal of Combinatorial Theory, Series B, 1972 AbstractWe call a degree sequence graphic (respectively, k-factorable, connected k-factorable) if there exists a graph (respectively, a graph with a k-factor, a graph with a connected k-factor) with the given degree sequence. In this paper we give a necessary and sufficient condition for a k-factorable sequence to be connected k-factorable when k ⩾ 2 ...
Ramachandra Rao, A, Rao, S.B
openaire +1 more source
FEBS Letters, EarlyView.This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley +1 more source
Informatica, 2019 Assume that we are given two graphic sequences, $\pi_1$ and $\pi_2$. We consider conditions for $\pi_1$ and $\pi_2$ which guarantee that there exists a simple graph $G_2$ realizing $\pi_2$ such that $G_2$ is the subgraph of any simple graph $G_1$ that realizes $\pi_1$.
Csaba, Béla, Vásárhelyi, Bálint
openaire +4 more sources
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
FEBS Letters, EarlyView.Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Hamiltonian-connected graphs and their strong closures
International Journal of Mathematics and Mathematical Sciences, 1997 Let G be a simple graph of order at least three. We show that G is Hamiltonian-connected if and only if its strong closure is Hamiltonian-connected. We also give an efficient algorithm to compute the strong closure of G.
Pak-Ken Wong
doaj +1 more source
Degree Sequences of Triangular Multigraphs
The Electronic Journal of CombinatoricsA simple graph is triangular if every edge is contained in a triangle. A sequence of integers is graphical if it is the degree sequence of a simple graph. Egan and Nikolayevsky recently conjectured that every graphical sequence whose terms are all at least 4 is the degree sequence of a triangular simple graph, and proved this in some special cases.
Talbot, John, Yan, Jun
openaire +2 more sources