Results 91 to 100 of about 1,235 (182)

Drug Repurposing Campaigns for Human Cytomegalovirus Identify a Natural Compound Targeting the Immediate-Early 2 (IE2) Protein: A Comment on “The Natural Flavonoid Compound Deguelin Inhibits HCMV Lytic Replication within Fibroblasts”

open access: yesViruses, 2019
Human cytomegalovirus (HCMV) is a ubiquitous herpesvirus that establishes a lifelong persistence in the host through both chronic and latent states of infection [...]
Beatrice Mercorelli   +4 more
doaj   +1 more source

Deguelin exerts anticancer activity of human gastric cancer MGC-803 and MKN-45 cells in vitro

open access: yesInternational Journal of Molecular Medicine, 2018
During the pathogenesis of gastric cancer, Akt signaling is considered as a pivotal inducer of gastric cancer development. Here we report the identification of anticancer activities of deguelin, a natural agent that inhibits Akt signaling.
Wen Kang   +3 more
semanticscholar   +1 more source

Deguelin suppresses angiogenesis in human hepatocellular carcinoma by targeting HGF-c-Met pathway

open access: yesOncoTarget, 2017
Angiogenesis plays a crucial role in the development of human hepatocellular carcinoma (HCC). In the present study, we found a natural compound, deguelin, has a profound anti-angiogenesis effect on HCC.
Ming Li   +7 more
semanticscholar   +1 more source

Total Synthesis of dl-Deguelin

open access: yesAgricultural and Biological Chemistry, 1960
FUKAMI, Hiroshi   +3 more
openaire   +3 more sources

Correction: A Novel Derivative of Deguelin [PDF]

open access: yesCancer Prevention Research, 2009
openaire   +1 more source

Deguelin`in deneysel meme kanseri tedavisindeki etkinliğinin araştırılması

open access: yes, 2021
Breast cancer is the second most common type of cancer among women in the USA and it is one of the most studied cancer type in the world. As an alternative for the standard treatment used in breast cancer there is a need for agents which are more potent and have less toxicity.
openaire   +1 more source

Abstract 2088 Investigating the conditional lethality of deguelin in blood cancer cells

open access: yesJournal of Biological Chemistry
Gavin Chang   +2 more
semanticscholar   +1 more source

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