Results 1 to 10 of about 728 (182)

Rotenoids and Isoflavones from Xeroderris stuhlmannii (Taub.) Mendonça & E.P. Souza and Their Biological Activities [PDF]

Molecules, 2023
The phytochemical study of the ethanolic extract of the leaf of Xeroderris stuhlmannii led to the isolation of five hitherto unreported compounds including two isoflavones (1–2), and three rotenoids (3–5), along with eight known isoflavonoid derivatives (
Livie Blondèle Kenou Mekuete, Willifred Dongmo Tékapi Tsopgni, Augustine Kuinze Nkojap, Jacquy Joyce Wanche Kojom, Timo D. Stark, Yannick Fouokeng, Alain Bertrand Dongmo, Léon Tapondjou Azeufack, Anatole Guy Blaise Azebaze   +8 more
doaj   +3 more sources

Anticholinesterase Activity of Methanolic Extract of Amorpha fruticosa Flowers and Isolation of Rotenoids and Putrescine and Spermidine Derivatives [PDF]

Plants
Five putrescine and spermidine derivatives (1–5) together with five rotenoids (6–10) were isolated from a methanolic extract of the flowers of A. fruticosa that displayed promising inhibition of 76.0 ± 1.9% for AChE and 90.0 ± 4.0% for BuChE at a ...
Dagmar Jankovská, Nikol Jurčová, Renata Kubínová, Jiří Václavík, Emil Švajdlenka, Anna Mascellani, Petr Maršík, Kateřina Bouzková, Milan Malaník   +8 more
doaj   +3 more sources

New Class of Tyrosinase Inhibitors, Rotenoids, from Amorpha fruticosa [PDF]

ACS Omega, 2023
A series of rotenoids including a new one from the seeds of Amorpha fruticosa were found to have significant potential as tyrosinase inhibitors. All of the isolated rotenoids (1–6) displayed inhibitory activity against tyrosinase, both as a monophenolase
Si Won Moon, Jeong Yoon Kim, Seung Hwan Lee, Se Young Im, Gihwan Lee, Ki Hun Park   +5 more
doaj   +3 more sources

Inhibition of adenovirus transport from the endosome to the cell nucleus by rotenone [PDF]

Frontiers in Pharmacology, 2023
Regardless of the clinical impact of human adenovirus (HAdV) infections in the healthy population and its high morbidity in immunosuppressed patients, a specific treatment is still not yet available.
María Balsera-Manzanero, Francesca Ghirga, Ana Ruiz-Molina, Mattia Mori, Jerónimo Pachón, Jerónimo Pachón, Bruno Botta, Elisa Cordero, Elisa Cordero, Elisa Cordero, Deborah Quaglio, Javier Sánchez-Céspedes, Javier Sánchez-Céspedes   +12 more
doaj   +2 more sources

Study on the absolute configuration and biological activity of rotenoids from the leaves and twigs of Millettia pyrrhocarpa Mattapha, Forest & Hawkins, sp. Nov [PDF]

BMC Complementary Medicine and Therapies, 2023
Background M. pyrrhocarpa is a new plant in the Fabaceae: Faboideae family that is found in Thailand. A literature search revealed that the Milletia genus is rich in bioactive compounds possessing a wide range of biological activities.
Suda Sananboonudom, Atchara Kaewnoi, Wilart Pompimon, Samroeng Narakaew, Suwadee Jiajaroen, Kittipong Chainok, Narong nuntasaen, Kanoknetr Suksen, Arthit Chairoungdua, Jitra Limthongkul, Chanita Naparswad, Suttiporn Pikulthong, Puttinan Meepowpan, Boonthawan Wingwon, Nichapa Charoenphakinrattana, Phansuang Udomputtimekakul   +15 more
doaj   +2 more sources

Chitosan nanocomposite containing rotenoids: an alternative bioinsecticidal approach for the management of Aedes aegypti [PDF]

Beilstein Journal of Nanotechnology
Climate change has intensified the proliferation of disease vectors, such as Aedes aegypti, the primary transmitter of dengue, chikungunya, and zika viruses.
Maria A. A. Bertonceli, Vitor D. C. Cristo, Ivo J. Vieira, Francisco J. A. Lemos, Arnoldo R. Façanha, Raimundo Braz-Filho, Gustavo V. T. Batista, Luis G. M. Basso, Sérgio H. Seabra, Thalya S. R. Nogueira, Felipe F. Moreira, Arícia L. E. M. Assis, Antônia E. A. Oliveira, Kátia V. S. Fernandes   +13 more
doaj   +2 more sources

In Silico Research of New Therapeutics Rotenoids Derivatives against Leishmania amazonensis Infection [PDF]

Biology, 2022
Yearly, 1,500,000 cases of leishmaniasis are diagnosed, causing thousands of deaths. To advance in its therapy, we present an interdisciplinary protocol that unifies ethnobotanical knowledge of natural compounds and the latest bioinformatics advances to ...
Adrián Vicente-Barrueco, Ángel Carlos Román, Trinidad Ruiz-Téllez, Francisco Centeno   +3 more
doaj   +2 more sources

Amorphigenin from Amorpha fruticosa L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent- and AMPK-Dependent Manner [PDF]

Current Issues in Molecular Biology, 2022
In this study, we investigated the depigmentation effect of Amorpha fruticosa L. root extract (RE), an herbal medicine. A. fruticosa RE significantly induced depigmentation in α-MSH-treated B16F10 cells at noncytotoxic concentrations.
Ki Won Lee, Dang Thi Nguyen, Minju Kim, Si Hyeon Lee, Seyeon Lim, Jisu Kim, Ki Hun Park, Jeong Yoon Kim, Jiyun Yoo, Cheol Hwangbo, Kwang Dong Kim   +10 more
doaj   +2 more sources

Fabaceae Flavonoids Beyond the Commonplace: A Review of Chemical Diversity, Pharmacological Activities, Mass Spectrometric Profiling and In Silico Insights into Their Subclasses [PDF]

Plants
Fabaceae family is recognized as a prolific flavonoid producer, including some unusual flavonoid skeletons. Although classic flavonoids have well-established biological properties in the literature, these unusual compounds remain underinvestigated. Based
Ana Rita Rodrigues de Almeida Silva Brilhante, Gabriela Ribeiro de Sousa, Ana Karoline Silva de Aquino-Vital, Natanael Teles Ramos de Lima, Ranna Beatris de Lima Souza, Thalisson Amorim de Souza, Marcus Tullius Scotti, José Maria Barbosa Filho, Josean Fechine Tavares, Marcelo Sobral da Silva   +9 more
doaj   +2 more sources

Correlation between phytocompounds and pharmacological activities of Boerhavia diffusa Linn with traditional-ethnopharmacological insights

Phytomedicine Plus, 2022
Background: : The human body is almost 70% water and fluid imbalance has been a classic symptom of severe underlying conditions, i.e., hepatic disorders, kidney disorders, cardiovascular disease and inflammation. Boerhavia diffusa Linn.
Praveen Kumar Gaur, Sameer Rastogi, Kanak Lata   +2 more
doaj   +1 more source