Results 11 to 20 of about 759 (134)

Ethnomedicinal Practices of the Fabaceae Family in Tanzania: A Systematic Review. [PDF]

ScientificWorldJournal
This study is aimed at reviewing the ethnomedicinal, phytochemical and pharmacological properties of Fabaceae species used as sources of traditional medications in Tanzania. Using the Systematic Reviews and Meta‐Analyses (PRISMA) methodology, a comprehensive review was conducted on Fabaceae species used by Tanzanians through electronic databases such ...
Kacholi DS.
europepmc   +2 more sources

Rotenoids from Tephrosia toxicaria with larvicidal activity against Aedes aegypti, the main vector of dengue fever [PDF]

Química Nova, 2012
In the search for new larvicides from plants, we have investigated the potential activity of the rotenoids deguelin (1), 12a-hydroxy-α-toxicarol (2) and tephrosin (3), isolated from the bioactive ethanol extract of roots of Tephrosia toxicaria Pers ...
Jackson Nunes e Vasconcelos, Gilvandete Maria Pinheiro Santiago, Jefferson Queiroz Lima, Jair Mafezoli, Telma Leda Gomes de Lemos, Francisca Renata Lopes da Silva, Mary Anne Sousa Lima, Antônia Torres Ávila Pimenta, Raimundo Braz-Filho, Angela Martha Campos Arriaga, Dari Cesarin-Sobrinho   +10 more
doaj   +2 more sources

Biflavonoid toxicarine, rotenoids and a flavanone from the roots of Tephrosia toxicaria [PDF]

Semina: Ciências Exatas e Tecnológicas, 2020
For the first time the structural determination of the biflavonoid, 4-H-2,3-dihydro-1-benzopyran-4-one-6-[2-phenyl-8-(3-methyl-2-butenyl)-5,7-dimethoxy-2-H-3,4-dihydro-1-benzopiran-4-yl)-5,7-dihydroxy-8-(3-methyl-2-butenyl)-2-phenyl, named toxicarine (1)
Cesar Cornélio Andrei, Terezinha de Jesus Faria, Adriana Aparecida Bosso Tomal, Pedro Renato Anizelli, Raimundo Braz-Filho   +4 more
doaj   +2 more sources

The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus. [PDF]

Chem Biodivers
The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Mykhailenko O, Ivanauskas L, Georgiyants V, Gudžinskas Z.   +3 more
europepmc   +2 more sources

In Silico Research of New Therapeutics Rotenoids Derivatives against Leishmania amazonensis Infection [PDF]

Biology, 2022
Yearly, 1,500,000 cases of leishmaniasis are diagnosed, causing thousands of deaths. To advance in its therapy, we present an interdisciplinary protocol that unifies ethnobotanical knowledge of natural compounds and the latest bioinformatics advances to ...
Adrián Vicente-Barrueco, Ángel Carlos Román, Trinidad Ruiz-Téllez, Francisco Centeno   +3 more
doaj   +2 more sources

Amorphigenin from Amorpha fruticosa L. Root Extract Induces Autophagy-Mediated Melanosome Degradation in mTOR-Independent- and AMPK-Dependent Manner [PDF]

Current Issues in Molecular Biology, 2022
In this study, we investigated the depigmentation effect of Amorpha fruticosa L. root extract (RE), an herbal medicine. A. fruticosa RE significantly induced depigmentation in α-MSH-treated B16F10 cells at noncytotoxic concentrations.
Ki Won Lee, Dang Thi Nguyen, Minju Kim, Si Hyeon Lee, Seyeon Lim, Jisu Kim, Ki Hun Park, Jeong Yoon Kim, Jiyun Yoo, Cheol Hwangbo, Kwang Dong Kim   +10 more
doaj   +2 more sources

Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells. [PDF]

J Nat Prod, 2020
Prostate cancer is one of the leading causes of cancer-related death in men. The identification of new therapeutics to selectively target prostate cancer cells is therefore vital.
Russell DA, Bridges HR, Serreli R, Kidd SL, Mateu N, Osberger TJ, Sore HF, Hirst J, Spring DR.   +8 more
europepmc   +3 more sources

Phytochemistry and Pharmacological Potential of the Genus Dalea: Current Evidence and Future Directions [PDF]

Pharmaceuticals
The genus Dalea (Fabaceae) comprises approximately 188 recognized species distributed mainly in arid and semi-arid regions of the American continent, where several species have been traditionally used in folk medicine for the treatment of ...
Renata Solis-Peña, Vanessa Lizbeth Correa-Macias, Hania Lizeth Peralez-Olguin, Dalia Lizbeth Martínez-Medellín, Andrea Melissa González-Rodríguez, Lizeth Guadalupe Campos-Muzquiz, Lissethe Palomo-Ligas, Sendar Daniel Nery-Flores   +7 more
doaj   +2 more sources

Fabaceae Flavonoids Beyond the Commonplace: A Review of Chemical Diversity, Pharmacological Activities, Mass Spectrometric Profiling and In Silico Insights into Their Subclasses [PDF]

Plants
Fabaceae family is recognized as a prolific flavonoid producer, including some unusual flavonoid skeletons. Although classic flavonoids have well-established biological properties in the literature, these unusual compounds remain underinvestigated. Based
Ana Rita Rodrigues de Almeida Silva Brilhante, Gabriela Ribeiro de Sousa, Ana Karoline Silva de Aquino-Vital, Natanael Teles Ramos de Lima, Ranna Beatris de Lima Souza, Thalisson Amorim de Souza, Marcus Tullius Scotti, José Maria Barbosa Filho, Josean Fechine Tavares, Marcelo Sobral da Silva   +9 more
doaj   +2 more sources

17-epi-Melianodiol, a new protolimonoid from Melia azedarach fruits, exhibits larvicidal activity and is associated with oxidative imbalance and midgut epithelial damage in Aedes aegypti larvae. [PDF]

Pest Manag Sci
The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Soares KDC, Nogueira TSR, Bertonceli MAA, da Silva Robaina RR, da Rocha LO, Lemos FJA, Fernandes KVS, Braz-Filho R, Curcino Vieira IJ.   +8 more
europepmc   +2 more sources