Phytoestrogens are naturally occurring nonsteroidal phenolic plant compounds that, due to their molecular structure and size, resemble vertebrate steroids estrogens. This review is focused on plant flavonoids isoflavones, which are ranked among the most estrogenic compounds.
Ludmila Křížová +3 more
exaly +6 more sources
Effect of soy in men with type 2 diabetes mellitus and subclinical hypogonadism: a randomised controlled study [PDF]
Context: Isoflavones found in soy products have a chemical structure similar to estrogen, leading to concerns of an adverse estrogenic effect in men, particularly in those with type 2 diabetes mellitus (T2DM) who have low testosterone levels due to ...
Atkin, Stephen L. +5 more
core +1 more source
Preliminary investigation of the effects of long-term dietary intake of genistein and daidzein on hepatic histopathology and biochemistry in domestic cats (Felis catus) [PDF]
Dietary isoflavones have been hypothesised to play a role in hepatic veno-occlusive disease in captive exotic felids, although empirical evidence is lacking. This study aimed to investigate the effect of long-term (>1 year) dietary genistein and daidzein
Cave, NJ +4 more
core +1 more source
Isoflavones in gynecology [PDF]
SUMMARY
Carbonel,Adriana Aparecida Ferraz +8 more
openaire +3 more sources
Soy protein improves cardiovascular risk in subclinical hypothyroidism : a randomized double-blinded crossover study [PDF]
© 2017 Endocrine Society. Background: Soy protein with isoflavones appears to have an adverse effect on thyroid function, but it is not known whether it is the protein or isoflavone component that is deleterious.
Atkin, Stephen L. +4 more
core +1 more source
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H +37 more
core +1 more source
Near Infrared Reflectance Spectroscopy (NIRS) Determination of Isoflavone Contents for Selected Soybean Accessions [PDF]
Soybean isoflavones are of considerable interest in relation to their possible health effects in human diets. The rapid and economical determination of soybean isoflavone concentrations is essential for the investigation and development of soybean health
I. C. Baianu +3 more
core +2 more sources
The effect of soy phytoestrogen supplementation on thyroid status and cardiovascular risk markers in patients with subclinical hypothyroidism: A randomized, double-blind, crossover study [PDF]
Context: There is concern whether soy phytoestrogens may affect thyroid function. If true, soy phytoestrogens may be expected to have a greater impact in subjects with subclinical hypothyroidism.
Atkin, Stephen L. +6 more
core +2 more sources
5-Hydroxy-3-(4-hydroxyphenyl)-8,8-dimethyl-6- (3-methylbut-2-enyl)pyrano[2,3-h]chromen-4-one [PDF]
Natural and semi-synthetic compounds are being studied as novel phosphodiesterase 5 (PDE5) inhibitors for the treatment of erectile dysfunction, pulmonary hypertension, and lower urinary symptoms.
Ongaro, Alberto +2 more
core +1 more source
A staged screening of registered drugs highlights remyelinating drug candidates for clinical trials [PDF]
There is no treatment for the myelin loss in multiple sclerosis, ultimately resulting in the axonal degeneration that leads to the progressive phase of the disease.
Agresti, C. +11 more
core +2 more sources

