Results 1 to 10 of about 26,245 (119)
Genistein as a Potential Anticancer Agent against Ovarian Cancer
Journal of Traditional and Complementary Medicine, 2012 Genistein is known as the major component of isoflavone, which is present in high-soy diets. Genistein has received much attention because of its chemopreventive and therapeutic effects on various types of cancers.
Hee Seung Kim +2 more
exaly +3 more sources
Aquaculture Reports, 2022 Genistein exhibits anti-diabetic and anti-lipogenic effects in mammals, however, there are rare reports on the effects of genistein on glucose and lipid metabolism in fish.
Liping Yang +8 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 Genistein is a natural isoflavone with pharmacological or potentially anti-tumor properties. However, the resistance of cancer cells to genistein remains a major obstacle.
Tianyu Li +6 more
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The Role of Genistein in Mammalian Reproduction
Molecules, 2023 Genistein is a natural compound belonging to flavonoids, having antioxidant, anti-inflammatory, and anti-neoplastic properties. Genistein is considered a phytoestrogen.
Gabriella Guelfi +8 more
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Molecules, 2023 Previous studies have provided evidence that genistein exerts a therapeutic effect on different tumor cells. However, the mechanism of action of genistein against cervical cancer cells remains largely unknown. The aim of this study was to comprehensively
Tingting Chen +4 more
doaj +1 more source
Inhibition of castration-resistant prostate cancer growth by genistein through suppression of AKR1C3
Food & Nutrition Research, 2023 Background: Prostate cancer is the second leading cause of cancer-related death among males in America. The patients’ survival time is significantly reduced after prostate cancer develops into castration-resistant prostate cancer (CRPC).
Xiaoping Yu +6 more
doaj +1 more source
Nutrikinetic study of genistein metabolites in ovariectomized mice. [PDF]
PLoS ONE, 2017 This study was designed to evaluate the effect of ovariectomy on nutrikinetics of genistein metabolites. To characterize the time-dependent changes in genistein metabolite concentrations, we identified 13 genistein metabolites using ultra-performance ...
Da-Hye Lee +8 more
doaj +1 more source
Involvement of Caspase-3 Pathway in Anti-cancer Properties of Genistein in AGS Gastric Cancer Cell Line is Still Enigmatic [PDF]
Avicenna Journal of Medical Biochemistry, 2022 Background: Genistein is an isoflavone that has been reported to have various anti-cancer properties. Objectives: This study aimed to reveal whether or not the anti-cancer properties of genistein in AGS gastric cancer cell line were mediated through ...
Neda Ghasemkhani +4 more
doaj +1 more source
Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein
Neural Regeneration Research, 2018 Genistein, a potent antioxidant compound, protects dopaminergic neurons in a mouse model of Parkinson's disease. However, the mechanism underlying this action remains unknown.
Huan-Cheng Wu +9 more
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Frontiers in Nutrition, 2022 IntroductionInsulin signaling via the insulin receptor (IR) may be associated with the amelioration of diet-induced metabolic syndrome. Genistein, a soy isoflavone, has been suggested to play a role in the amelioration of high-fat diet-induced metabolic ...
Nana Zhang +6 more
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