Results 11 to 20 of about 61,268 (292)
Genistein Targets STING-Driven Antiviral Responses
mBio, 2022 Cytoplasmic detection of DNA by cyclic GMP-AMP (cGAMP) synthase (cGAS) is an essential component of antiviral responses. Upon synthesis, cGAMP binds to the stimulator of interferon (IFN) genes (STING) in infected and adjacent cells through intercellular ...
Tomalika R. Ullah +9 more
doaj +4 more sources
Synthesizing efficacious genistein in conjugation with superparamagnetic Fe3O4 decorated with bio-compatible carboxymethylated chitosan against acute leukemia lymphoma [PDF]
, 2020 Background Genistein (C15H10O5) is a soy isoflavone with anti-cancer properties such as inhibition of cell growth, proliferation and tumor invasion, but effective dosage against hematopoietic malignant cells was not in non-toxic range.
Ghasemi Goorbandi, Rachel +2 more
core +3 more sources
Genistein isoflavone glycoconjugates in sour cherry cultivars : Prunus cerasus L. [PDF]
, 2013 Although the isoflavone genistein has well-established health-beneficial effects, it is not a major component of Western diet, since soy consumption, the main dietary source of genistein, is low in these populations.
László Abrankó +4 more
openalex +2 more sources
Nutrikinetic study of genistein metabolites in ovariectomized mice. [PDF]
PLoS ONE, 2017 This study was designed to evaluate the effect of ovariectomy on nutrikinetics of genistein metabolites. To characterize the time-dependent changes in genistein metabolite concentrations, we identified 13 genistein metabolites using ultra-performance ...
Da-Hye Lee +8 more
doaj +1 more source
Frontiers in Nutrition, 2022 IntroductionInsulin signaling via the insulin receptor (IR) may be associated with the amelioration of diet-induced metabolic syndrome. Genistein, a soy isoflavone, has been suggested to play a role in the amelioration of high-fat diet-induced metabolic ...
Nana Zhang +6 more
doaj +1 more source
Genistein-induced mir-23b expression inhibits the growth of breast cancer cells [PDF]
, 2015 Aim of the study: Genistein, an isoflavonoid, plays roles in the inhibition of protein tyrosine kinase phosphorylation, induction of apoptosis, and cell differentiation in breast cancer.
Avci, C.B. +6 more
core +2 more sources
Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein
Neural Regeneration Research, 2018 Genistein, a potent antioxidant compound, protects dopaminergic neurons in a mouse model of Parkinson's disease. However, the mechanism underlying this action remains unknown.
Huan-Cheng Wu +9 more
doaj +1 more source
Redox Report, 2022 Objective Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein in modulating versican/platelet derived growth factor (PDGF ...
Yousra M. El-Far +4 more
doaj +1 more source
Involvement of Caspase-3 Pathway in Anti-cancer Properties of Genistein in AGS Gastric Cancer Cell Line is Still Enigmatic [PDF]
Avicenna Journal of Medical Biochemistry, 2022 Background: Genistein is an isoflavone that has been reported to have various anti-cancer properties. Objectives: This study aimed to reveal whether or not the anti-cancer properties of genistein in AGS gastric cancer cell line were mediated through ...
Neda Ghasemkhani +4 more
doaj +1 more source
The obesogenic side of Genistein
Frontiers in Endocrinology, 2023 Genistein (GN) has been highly recommended for its medicinal properties like anticancer, antidiabetic, antihyperlipidemic, antiviral, and antioxidant activities among others. Recently, scientists realized that Genistein is an endocrine disruptor. It is an obesogen that interferes with the endocrine system causing obesity through many mechanisms like ...
Jia Xiang +14 more
openaire +3 more sources