Results 31 to 40 of about 61,268 (292)
Genistein prevents bone loss in type 2 diabetic rats induced by streptozotocin
Food & Nutrition Research, 2020 Background: Diabetic osteoporosis has become a severe public health problem in the aging societies. Genistein has been reported to play an important role in preventing and treating metabolic diseases via its anti-inflammatory, antioxidant, anti ...
Rongrong Lu +3 more
doaj +1 more source
Genistein-3′-sulfonic acid dihydrate [PDF]
Acta Crystallographica Section E Structure Reports Online, 2009 IN THE TITLE COMPOUND [SYSTEMATIC NAME: 5-(5,7-dihydr-oxy-4-oxo-4H-chromen-yl)-2-hydroxy-benzene-sulfonic acid dihydrate], C(15)H(10)O(8)S·2H(2)O, the benzopyran-one ring is not coplanar with the phenyl ring, the dihedral angle between them being 41.35 (3)°.
Zhang, Chang-Peng +4 more
openaire +2 more sources
Improvement of genistein content in solid genistein/-cyclodextrin complexes β [PDF]
Química Nova, 2010 Genistein:β-cyclodextrin complexes with high drug loading (19.22%) were prepared by freeze-drying and characterized by differential scanning calorimetry and hydrogen nuclear magnetic resonance spectroscopy. The spatial configuration of the complex was proposed by means of 2D-NOESY experiment combined with molecular modeling.
Xavier, Clarissa R. +9 more
openaire +3 more sources
Activation of Chloride Secretion by Isoflavone Genistein in Endometrial Epithelial Cells
Cellular Physiology and Biochemistry, 2013 Background /Aim: Genistein, the most active isoflavone found primarily in soybeans, alters ion transport functions in intestinal and airway epithelia.
Chatsri Deachapunya +1 more
doaj +1 more source
Effect of soy in men with type 2 diabetes mellitus and subclinical hypogonadism: a randomised controlled study [PDF]
, 2016 Context: Isoflavones found in soy products have a chemical structure similar to estrogen, leading to concerns of an adverse estrogenic effect in men, particularly in those with type 2 diabetes mellitus (T2DM) who have low testosterone levels due to ...
Atkin, Stephen L. +5 more
core +1 more source
Genistein: A Potent Natural Antiandrogen [PDF]
Clinical Chemistry, 2000 Flavonoids and other polyphenolic natural compounds have attracted much attention as candidate cancer preventive and anticarcinogenic agents, as well as antiatherogenic and antioxidant compounds (1). Although the public now consumes these compounds in substantial amounts from dietary sources, food supplements, and more recently, as “nutraceutical ...
R S, Rosenberg Zand +2 more
openaire +2 more sources
PLoS ONE, 2019 The purpose of this study was to evaluate the response of estrogen target cells to a series of isoflavone glucosides and aglycones from Genista halacsyi Heldr.
Nikolas Fokialakis +11 more
doaj +1 more source
A highly selective cell-based fluorescent biosensor for genistein detection
Engineering Microbiology, 2023 Genistein, an isoflavone found mainly in legumes, has been shown to have numerous health benefits for humans. Therefore, there is substantial interest in producing it using microbial cell factories.
Lucy Fang-I Chao +2 more
doaj +1 more source
Oncogenic microRNA-4534 regulates PTEN pathway in prostate cancer. [PDF]
, 2016 Prostate carcinogenesis involves alterations in several signaling pathways, the most prominent being the PI3K/AKT pathway. This pathway is constitutively active and drives prostate cancer (PCa) progression to advanced metastatic disease. PTEN, a critical
Chowdhary, Harshika +19 more
core +2 more sources
Agonistic and antagonistic estrogens in licorice root (Glycyrrhiza glabra) [PDF]
, 2011 The roots of licorice (Glycyrrhiza glabra) are a rich source of flavonoids, in particular, prenylated flavonoids, such as the isoflavan glabridin and the isoflavene glabrene.
Bovee, T.F.H. +7 more
core +2 more sources