Results 21 to 30 of about 25,462 (209)
Neuroprotective effects of genistein on SH-SY5Y cells overexpressing A53T mutant α-synuclein
Neural Regeneration Research, 2018 Genistein, a potent antioxidant compound, protects dopaminergic neurons in a mouse model of Parkinson's disease. However, the mechanism underlying this action remains unknown.
Huan-Cheng Wu +9 more
doaj +1 more source
Redox Report, 2022 Objective Genistein is a recognized isoflavone present in soybeans with antioxidant, anti-inflammatory, antiangiogenic and antitumor activities. This study aimed to test ability of genistein in modulating versican/platelet derived growth factor (PDGF ...
Yousra M. El-Far +4 more
doaj +1 more source
Involvement of Caspase-3 Pathway in Anti-cancer Properties of Genistein in AGS Gastric Cancer Cell Line is Still Enigmatic [PDF]
Avicenna Journal of Medical Biochemistry, 2022 Background: Genistein is an isoflavone that has been reported to have various anti-cancer properties. Objectives: This study aimed to reveal whether or not the anti-cancer properties of genistein in AGS gastric cancer cell line were mediated through ...
Neda Ghasemkhani +4 more
doaj +1 more source
The Flavonoids Daidzein and Genistein Induce Wall-Deficient Cell Formation in Streptomyces coelicolor Under Hyperosmotic Stress. [PDF]
Microb BiotechnolPlant‐derived isoflavones (daidzein and genistein) function as chemical signals that induce stress‐dependent formation of wall‐deficient cells (S‐cells) in Streptomyces coelicolor. ABSTRACT Streptomycetes exhibit a complex multicellular life cycle, including programmed cell death and hyphal differentiation, and can generate extracellular vesicles and ...
Valdés-Chiara P +3 more
europepmc +2 more sources
Daidzein and genistein contents of vegetables [PDF]
British Journal of Nutrition, 2000 Food samples (n114) were prepared from vegetables commonly eaten in Europe. The glycosidic forms of the phyto-oestrogens daidzein and genistein were extracted from the dried foods into aqueous methanol. The isoflavones were quantified by GC–MS after hydrolytic removal of any conjugated carbohydrate.
Liggins, J +5 more
openaire +3 more sources
Genistein upregulates LDLR levels via JNK-mediated activation of SREBP-2
Food & Nutrition Research, 2016 Background: Genistein has been proved in vitro and in vivo to lower LDLR level. It is also widely consumed and implicated for its anti-atherogenic effects.
Medicia Kartawijaya +3 more
doaj +1 more source
Antioxidants, 2019 We examined the anti-cancer effect of genistein, a soy-derived isoflavone, in human bladder transitional cell carcinoma T24 cells. According to our data, genistein induced G2/M phase arrest of the cell cycle and apoptosis.
Cheol Park +12 more
doaj +1 more source
Formation of phosphoglycosides in Caenorhabditis elegans: a novel biotransformation pathway. [PDF]
PLoS ONE, 2012 BACKGROUND: Caenorhabditis elegans (C. elegans) has become a widely used model to explore the effect of food constituents on health as well as on life-span extension.
Sebastian T Soukup +5 more
doaj +1 more source
Daidzein and genistein content of cereals [PDF]
European Journal of Clinical Nutrition, 2002 To analyse 75 cereals and three soy flours commonly eaten in Europe for the phytoestrogens daidzein and genistein.The phytoestrogens daidzein and genistein were extracted from dried foods, and the two isoflavones quantified after hydrolytic removal of any conjugated carbohydrate.
J, Liggins +3 more
openaire +2 more sources
Genistein Exposure Interferes with Pharmacokinetics of Celecoxib in SD Male Rats by UPLC-MS/MS
Biochemistry Research International, 2017 Objective. To discuss the effects of genistein on the metabolism of celecoxib in vitro and in vivo. Method. In vitro, the effects of genistein on the metabolism of celecoxib were studied using rat and human liver microsomes.
Xiang Zheng +5 more
doaj +1 more source