Results 41 to 50 of about 29,683 (224)

Higher usual dietary intake of phytoestrogens is associated with lower aortic stiffness in postmenopausal women [PDF]

open access: yes, 2002
Objective¿ Phytoestrogens have been postulated to protect against cardiovascular diseases, but few studies have focused on the effect of Western dietary phytoestrogen intake.
Pijpelink, A   +16 more
core   +2 more sources

An Artificially Selected Cytokinin‐Pathway Transcription Factor Balances Soybean Yield and Pathogen Resistance

open access: yesAdvanced Science, EarlyView.
A cytokinin pathway transcription factor, RR2b, was artificially selected during soybean domestication and improvement based on its differential transcriptional activity, which correlates with ATT repeat polymorphisms in its promoter. RR2b balances yield and defense by fine‐tuning its expression level and offers a promising target for decoupling trade ...
Qun Ma   +11 more
wiley   +1 more source

Gut Microbial Release of Ferulic Acid From Germinated Quinoa Alleviates Obesity‐Associated Cognitive Impairment by Activating Hippocampal Mitophagy Associated with PINK1/Parkin Pathway

open access: yesAdvanced Science, EarlyView.
Liberation of ferulic acid by gut microbial feruloyl esterase mediates cognitive enhancement of germinated quinoa (GQF) on obese mice. Ferulic acid enriched in GQF is released by gut microbes Roseburia hominis and R. intestinalis and subsequently mediates the neuroprotective effects of GQF on obesity‐induced cognitive decline by activating hippocampal ...
Yongli Lan   +11 more
wiley   +1 more source

Long‐Term Exposure to Isoflavones Alters the Hormonal Steroid Homeostasis‐Impairing Reproductive Function in Adult Male Wistar Rats

open access: yes, 2023
The consumption of isoflavones is gaining popularity worldwide due to their beneficial effects on health. However, isoflavones are considered to be endocrine disruptors and cause deleterious effects on hormone‐sensitive organs, especially in males ...
Crespo, Belen   +7 more
core   +1 more source

Isoflavones, genistein and daidzein, regulate mucosal immune response by suppressing dendritic cell function. [PDF]

open access: yesPLoS ONE, 2012
Lipopolysaccharide (LPS), a component of gram-negative bacterial cell walls, has been shown to have a strong adjuvant effect towards inhaled antigens contributing to airway inflammation.
John Wei   +4 more
doaj   +1 more source

Architecture‐Engineered Semi‐Crystalline Microporous Polymer Membranes for Precise Molecular Separation

open access: yesAdvanced Science, EarlyView.
Guided by a Random Forest model, a π–π‐driven ordered stacking strategy deploys functionally distinct substructures to restrict chain segment motion and increase free volume, while preserving the intermolecular interactions that maintain structural integrity.
Zi‐Meng Xu   +10 more
wiley   +1 more source

Advances in synthesizing plant-derived isoflavones and their precursors with multiple pharmacological activities using engineered yeasts

open access: yesMicrobial Cell Factories
Isoflavones such as daidzein and genistein are naturally occurring compounds found in plants such as legumes. They have diverse pharmacological activities, making them valuable in the food, pharmaceutical, and cosmetic industries.
Wenhui Niu   +4 more
doaj   +1 more source

A cross-sectional study of dietary and urinary soy isoflavones about coal-burning fluorosis in Guizhou, China

open access: yesFrontiers in Nutrition
ObjectivePrevious research showed soy isoflavones have antioxidant properties beneficial to bone health, but no epidemiological studies reported effects of soy isoflavones on fluorosis. Therefore, the aim of this study was to investigate the relationship
Hua Han   +12 more
doaj   +1 more source

Drought Stress Mediated Changes in Food Crops: Mechanisms and Remediation Strategies

open access: yesAdvanced Science, EarlyView.
This work presents a multi‐scale framework for flavonoid‐mediated drought tolerance in staple food crops, integrating ROS redox regulation, antioxidant defense, rhizosphere microbial interactions, and sustainable agronomic practices. This interdisciplinary model provides core insights to develop climate‐resilient cropping systems and enhance global ...
Xiaoyi Duan   +5 more
wiley   +1 more source

Puerarin‑Loaded pH‑Responsive ZIF‑90 Nanoparticles Ameliorate Osteoporosis via Enhancing H3K18 Lactylation and Suppressing Aberrant Osteoclast Activation

open access: yesAdvanced Science, EarlyView.
Schematic illustration of the mechanism by which ZIF‐90@PU alleviates osteoporosis via H3K18la‐mediated NFATc1 pathway suppression. ABSTRACT Osteoporosis is characterized by dysregulated osteoclast activity, leading to excessive bone resorption and structural damage.
Jiajia Lu   +5 more
wiley   +1 more source

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