The State of Knowledge of the Primary and Secondary Metabolites of the Iris Genus. [PDF]
The genus Iris L. (Iridaceae) comprises over 320 species, primarily found in the northern hemisphere. Iris species are important in horticulture, folklore and medicine, and contain a variety of primary and secondary metabolites with significant biological activity.
Mykhailenko O +3 more
europepmc +2 more sources
Hydroxylated Rotenoids Selectively Inhibit the Proliferation of Prostate Cancer Cells. [PDF]
Prostate cancer is one of the leading causes of cancer-related death in men. The identification of new therapeutics to selectively target prostate cancer cells is therefore vital.
Russell DA +8 more
europepmc +2 more sources
Drought Stress Inhibits the Accumulation of Rotenoids and the Biosynthesis of Drought-Responsive Phytohormones in <i>Mirabilis himalaica</i> (Edgew.) Heim Calli. [PDF]
Background: Mirabilis himalaica, distributed in the high-altitude, arid, and semi-arid regions of Xizang, exhibits great tolerance to drought, which is rich in rotenoids and other secondary metabolites.
Zhang S +8 more
europepmc +2 more sources
Antidiabetic and Cytotoxic Activities of Rotenoids and Isoflavonoids Isolated from Millettia pachycarpa Benth. [PDF]
A phytochemical investigation of the root and leaf extracts of Millettia pachycarpa Benth resulted in the isolation and identification of 16 compounds, including six rotenoids (1–6) and 10 prenylated isoflavonoids (7–16).
Suthiphasilp V +10 more
europepmc +2 more sources
Effect of Some Growth Regulators and Systemic Copper Complexes on Reducing Floral Malformation, Yield and Quality of "Alphonse" Mango (Mangifera indica L.) [PDF]
The present study was carried out during 2019 and 2020 seasons on Alphonse mango trees to evaluate the effect of some growth reg-ulators and systemic copper complexes on flo-ral malformation, yield and quality.
Abdelaty Aboelezz +3 more
doaj +1 more source
The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors
The Concise Guide to PHARMACOLOGY 2023/24 is the sixth in this series of biennial publications. The Concise Guide provides concise overviews, mostly in tabular format, of the key properties of approximately 1800 drug targets, and about 6000 interactions with about 3900 ligands.
Stephen P. H. Alexander +165 more
wiley +1 more source
Synthetic Studies on Rotenoids
A general cyclization reaction to dehydrorotenoids has been developed. Dehydrorotenone (III) and dehydrodeguelin (IV) were obtained in high yield from methyl derrisate (Vb) and methyl deguelate (VIb), respectively, by treatment with sodium ethoxide.
Nobuji Nakatani, Masanao Matsui
+6 more sources
A review on invasive false indigo bush (Amorpha fruticosa L.): Nuisance plant with multiple benefits
Amorpha fruticosa L. represents an invasive plant causing a nuisance and degrading native biodiversity on a variety of wet and mesic habitats throughout the Northern Hemisphere. On the other hand, the plant species possesses numerous beneficial applications including phytochemical and biocoenotic uses, as well as ecosystem services.
Jasna Grabić +4 more
wiley +1 more source
Derrisfolin A, a chemical inducer of regucalcin, attenuated lipopolysaccharide‐induced inflammatory responses in pancreatic MIN6 β‐cells. Regucalcin in MIN6 cells and RAW264.7 macrophages also blocks inflammatory interaction between both cells in a transwell coculture system.
Tomiyasu Murata +9 more
wiley +1 more source
Studying 400 T2DM patients without complication indicated: In T2DM patients without complication, the GPx and TAC levels decreased and the MDA level elevated. T2DM with neuropathy had lower levels of GSH, GPx, and TAC and higher levels of TOS, MDA, and OSI and a higher frequency of Keap1 AA genotype.
Farnaz Khalili +9 more
wiley +1 more source

