Results 21 to 30 of about 10,572 (223)

Teratogenicity/Fetotoxicity of DEHP in Mice [PDF]

Environmental Health Perspectives, 1982
The embryonic/fetotoxic effects of DEHP on pregnant mice (ddY-Slc female x CBA male) were studied. DEHP was administered orally in dosages of 0.05 ml/kg to 30.0 mg/kg on day 6, 7, 8, 9 or 10 of gestation. A single administration of DEHP over 0.1 ml/kg (1/300 of LD50) on day 7 of gestation decreased the numbers and the body weight of living fetuses ...
I, Tomita, Y, Nakamura, Y, Yagi, K, Tutikawa   +3 more
openaire   +2 more sources

Rapid Detection of Plasticizer Migration From UV-Aged PVC Films by DART-HRMS. [PDF]

Rapid Commun Mass Spectrom
ABSTRACT Rationale The migration of phthalate plasticizers from high‐volume polymers, such as poly(vinyl chloride) (PVC), raises significant toxicological concerns, particularly when materials are subjected to aging and environmental stress. As traditional monitoring techniques rely on time‐consuming solvent extraction and chromatographic methods that ...
Leite-Barbosa O, de Oliveira MFL, de Oliveira MG, Padilha MC, Veiga-Junior VF.   +4 more
europepmc   +2 more sources

Biodegradation of di(2-ethylhexyl) phthalate by a new bacterial consortium

Water Science and Technology, 2023
Di(2-ethylhexyl) phthalate (DEHP) with continuous high concentration was used as the sole carbon and energy source to isolate a new bacterial consortium (K1) from agricultural soil covered with plastic film for a long time.
Liangwei Kou, Hanyu Chen, Xueqi Zhang, Shaoqin Liu, Baozhong Zhang, Huina Zhu   +5 more
doaj   +1 more source

DEHP Down-Regulates Tshr Gene Expression in Rat Thyroid Tissues and FRTL-5 Rat Thyrocytes: A Potential Mechanism of Thyroid Disruption [PDF]

Endocrinology and Metabolism, 2021
Background Di-2-ethylhexyl phthalate (DEHP) is known to disrupt thyroid hormonal status. However, the underlying molecular mechanism of this disruption is unclear. Therefore, we investigated the direct effects of DEHP on the thyroid gland.
Min Joo Kim, Hwan Hee Kim, Young Shin Song, Ok-Hee Kim, Kyungho Choi, Sujin Kim, Byung-Chul Oh, Young Joo Park   +7 more
doaj   +1 more source

Di(2-ethylhexyl) phthalate mediates IL-33 production via aryl hydrocarbon receptor and is associated with childhood allergy development

Frontiers in Immunology, 2023
BackgroundFew studies assess cord blood biomarkers to predict prenatal exposure to di(2-ethylhexyl) phthalate (DEHP) on the development of allergic diseases later in childhood. IL-33 has been indicated to play an important role in allergic diseases.
Mei-Lan Tsai, Mei-Lan Tsai, Shih-Hsien Hsu, Shih-Hsien Hsu, Shih-Hsien Hsu, Li-Ting Wang, Wei-Ting Liao, Wei-Ting Liao, Yi-Ching Lin, Yi-Ching Lin, Yi-Ching Lin, Yi-Ching Lin, Chang-Hung Kuo, Chang-Hung Kuo, Ya-Ling Hsu, Ya-Ling Hsu, Ming-Chu Feng, Ming-Chu Feng, Fu-Chen Kuo, Fu-Chen Kuo, Chih-Hsing Hung, Chih-Hsing Hung, Chih-Hsing Hung, Chih-Hsing Hung, Chih-Hsing Hung   +24 more
doaj   +1 more source

Effects of typical phthalate esters on lipid metabolism in rats and its potential mechanism

环境与职业医学, 2022
BackgroundDi(2-ethylhexyl)phthalate (DEHP) and dibutyl phthalate (DBP) are representative environmental endocrine disruptors of phthalate esters (PAEs).
Rui ZHANG, Xiaozhen CHEN, Liping LI, Yue ZHU, Ling LI, Herong LIU, Xiaoming DE   +6 more
doaj   +1 more source

Impact of mold growth on di(2-ethylhexyl) phthalate emission from moist wallpaper

Heliyon, 2022
Flood damage can increase indoor concentrations of di(2-ethylhexyl) phthalate (DEHP) and molds in households with wallpaper. Wallpaper water content can affect its DEHP emission into indoor environments; however, the influence of mold growth on this DEHP
Nai-Tzu Chen, Ching-Hui Shih, Chien-Cheng Jung, Nai-Yun Hsu, Chung-Yu Chen, Ching-Chang Lee, Huey-Jen Su   +6 more
doaj   +1 more source

Subacute Exposure to an Environmentally Relevant Dose of Di-(2-ethylhexyl) Phthalate during Gestation Alters the Cecal Microbiome, but Not Pregnancy Outcomes in Mice

Toxics, 2021
Di-2-ethylhexyl phthalate (DEHP) is a plasticizer commonly found in polyvinyl chloride, medical equipment, and food packaging. DEHP has been shown to target the reproductive system and alter the gut microbiome in humans and experimental animals. However,
Karen Chiu, Shah Tauseef Bashir, Liying Gao, Jessica Gutierrez, Maria R. C. de Godoy, Jenny Drnevich, Christopher J. Fields, Isaac Cann, Jodi A. Flaws, Romana A. Nowak   +9 more
doaj   +1 more source

Release of Di-(2-ethylhexyl) Phthalate from Agricultural Plastic Film in the Karst Plateau Area and Its Effect on Film-covered Soil

Yankuang ceshi, 2019
BACKGROUND With the wide application of PAEs in plastic greenhouse and plastic film mulching cultivation techniques, the pollution of diethylhexyl phthalate (DEHP) in agricultural soils has become widespread in China.
ZHU Dan-ni, ZOU Sheng-zhang, ZHOU Chang-song, LIU Fei, XIE Hao, LU Hai-ping   +5 more
doaj   +1 more source

Mutagenic/carcinogenic potential of DEHP and MEHP. [PDF]

Environmental Health Perspectives, 1982
The mutagenic/carcinogenic activities of DEHP and MEHP were studied in bacteria and mammalian cells. MEHP but not DEHP exerted a dose-dependent DNA damaging effect to B. subtilis in Rec-assay. DEHP and MEHP showed mutagenic activities to S. typhimurium TA-100, with and without S-9 mix, respectively. MEHP produced not only the mutation in E. coli WP2B/r
I, Tomita, Y, Nakamura, N, Aoki, N, Inui
openaire   +3 more sources