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Impact of AGT rs5050(T>G) variants on associations between estradiol and angiotensinogen levels: Multi-Ethnic Study of Atherosclerosis (MESA). [PDF]
Lidani KCF +8 more
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Sex hormones and 14 autoimmune diseases: The causal relationship from a bidirectional 2-sample Mendelian randomization study. [PDF]
Tang R, You X, Yuan B, Ling Z, Li Y.
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Dehydroepiandrosterone – a neurosteroid
European Journal of Clinical Investigation, 2000Dehydroepiandrosteone (DHEA) and its sulfate ester (DHEAS) are the major secretory products of the human adrenal glands and serve as precursors for both androgenic and estrogenic steroids. DHEA/S concentrations are particularly high in the brain, and DHEA/S and related steroids can be synthesized de novo in brain glial cells.
Friess, E. +3 more
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Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate Dynamics in Obesity
Canadian Journal of Biochemistry, 1975Dehydroepiandrosterone (D) and dehydroepiandrosterone sulfate (DS) dynamics were studied in three obese female subjects following a single injection of [4-14C]D and [7α-3H]-DS tracers. Dynamic parameters were calculated simultaneously by both the urinary and blood method of compartmentalization. Estimates for the urinary secretion and production rates
T, Fehér, L, Halmy
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Dehydroepiandrosterone sulfate and dehydroepiandrosterone: neuroactive neurosteroids
Current Opinion in Endocrinology & Diabetes, 2000During the last five years, advances have been made in understanding of the role of dehydroepiandrosterone sulfate (DHEAS) and dehydroepiandrosterone (DHEA) in the central nervous system (CNS). It has become clear that the two molecules can be qualified as neurosteroids and neuroactive steroids.
Yvette Akwa, Etienne-Emile Baulieu
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Dehydroepiandrosterone Replacement Therapy
Seminars in Reproductive Medicine, 2004Dehydroepiandrosterone (DHEA) replacement therapy has attracted considerable attention over recent years. Significant beneficial effects of DHEA replacement have been reported in patients representing the pathophysiological model of complete DHEA deficiency, in other words, adrenal insufficiency (AI). This includes effects on well-being, energy levels,
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Dehydroepiandrosterone in gout
Steroids, 1964Abstract Butte and Marson (1) have reported normal 17-ketosteroid (17-KS) values for patients with gout, while Wolfson et al (2) reported decreased urinary values. Our study indicates that while the total urinary 17-KS of patients with this disease are normal, 3β-hydroxy-androst-5-en-17-one (dehydroepiandrosterone; DHA) could not be detected.
Jiří Sonka +2 more
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Testosterone, Dehydroepiandrosterone, and Dehydroepiandrosterone Sulfate in Hyperandrogenic Women
The Journal of Clinical Endocrinology & Metabolism, 1984Serum levels of testosterone (T), dehydroepiandrosterone (DHEA), and DHEA sulfate (DHEA-S) were measured in a group of 285 women with clinical signs of hyperandrogenism (hirsutism and/or acne). Levels of T were elevated in 75.8% of the patients, DHEA in 57.5%, and DHEA-S in 20%. Normal levels of all 3 androgens were found in 13.3%.
E, Steinberger +2 more
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