Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate in Alzheimer's Disease: A Systematic Review and Meta-Analysis [PDF]
Frontiers in Aging Neuroscience, 2019 Background and Purpose: Previous studies found inconsistent results for the relationship between Alzheimer's disease and the levels of dehydroepiandrosterone and dehydroepiandrosterone sulfate.
Xiongfeng Pan +2 more
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Relationship of body composition with cortisol and dehydroepiandrosterone sulfate levels in Korean men and women [PDF]
Journal of International Medical ResearchBackground Glucocorticoids, primarily cortisol, mediated by the hypothalamic–pituitary–adrenal axis, significantly influence metabolic responses, including insulin resistance, lipolysis, and body fat distribution.
Sat Byul Park
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Low serum dehydroepiandrosterone is associated with diabetic dyslipidemia risk in males with type 2 diabetes [PDF]
Frontiers in Endocrinology, 2023 ObjectiveSex steroid hormones are associated with the advancement of metabolic diseases such as dyslipidemia. This cross-sectional study aimed to investigate the relationship between dehydroepiandrosterone, dehydroepiandrosterone sulfate, androstenedione,
Shanshan Chen +4 more
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The metabolism of dehydroepiandrosterone sulfate and dehydroepiandrosterone
Aging Male, 1998 Dehydroepiandrosterone sulfate (DHEAS), one of the major secretory products of the adrenal glands, is cleared very slowly from the circulation with a t1/2 of 13.7 h and a metabolic clearance rate of 15.5 1/day. This slow metabolism is due, largely, to its strong binding to serum albumin, and its renal tubular reabsorption.
C Longcope
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Case Report: Adrenocortical adenoma harboring atypical subclinical Cushing’s syndrome with dehydroepiandrosterone sulfate transferase and cytochrome b5 expression in tumor cells [PDF]
Frontiers in EndocrinologySubclinical Cushing’s syndrome (SCS) is frequently encountered during the clinical evaluation of adrenal incidentalomas and is typically associated with reduced levels of serum dehydroepiandrosterone sulfate (DHEA-S).
Ichiro Abe +18 more
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Correlation of age and sex with urine dehydroepiandrosterone sulfate level in healthy Thai volunteers [PDF]
Practical Laboratory Medicine, 2021 Objective: Dehydroepiandrosterone sulfate (DHEAs), a prohormone secreted by the adrenal gland, plays a role in the synthesis of sex hormones, namely, androgen and estrogen.
Karnpimon Krorakai +6 more
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Low Serum Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate Are Associated With Coronary Heart Disease in Men With Type 2 Diabetes Mellitus [PDF]
Frontiers in Endocrinology, 2022 AimsSex hormones play an important role in the pathogenesis of cardiovascular disease (CVD). This cross-sectional study aimed to explore the associations of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) with coronary heart ...
Xinxin Zhang +7 more
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Reduced Dehydroepiandrosterone-Sulfate Levels in the Mid-Luteal Subphase of the Menstrual Cycle: Implications to Women’s Health Research [PDF]
Metabolites, 2022 The regulation of DHEA-sulfate by steroid sulfotransferase (SULT) and steryl-sulfatase (STS) enzymes is a vital process for the downstream formation of many steroid hormones. DHEA-sulfate is the most abundant steroid hormone in the human body; thus, DHEA-
Ajna Hamidovic +5 more
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Theriogenology Wild, 2023 Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are important estrogen precursors, secreted mainly by the adrenal cortex. At late gestation, both DHEA and DHEAS (DHEA(S)) are produced at high concentrations in some species due to the developing ...
Emilee N. Hart +2 more
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Behavioral correlates of dehydroepiandrosterone and dehydroepiandrosterone sulfate
Aging Male, 1998 The actions of dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) on the central nervous system have been described as neurotropic, excitatory, and neuromodulator and may form the basis of various psychological effects in humans. Two research strategies help to define a possible role for DHEA and DHEAS in human behavior: first, to
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