Serum Dehydroepiandrosterone, Dehydroepiandrosterone Sulfate, and Pregnenolone Sulfate Concentrations in Patients with Hyperthyroidism and Hypothyroidism [PDF]
Clinical Chemistry, 2000 AbstractBackground: Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) have been suggested to have protective effects against cardiovascular disease, cancer, immune-modulated diseases, and aging. We examined serum concentrations of DHEA, DHEA-S, and pregnenolone sulfate (PREG-S) in patients with thyroid dysfunction.Methods ...
N, Tagawa +8 more
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Physical Activity Influences Cortisol and Dehydroepiandrosterone (Sulfate) Levels in Older Adults: A Systematic Review and Meta-Analysis [PDF]
, 2022 Age-related changes affect the ratio between two steroid hormones of the hypothalamic-pituitary-adrenal axis, cortisol and dehydroepiandrosterone (sulfate) (DHEA[S]).
Ofosu, Esther F. +4 more
core +1 more source
Identification of steroid sulfate transport processes in the human mammary gland [PDF]
, 2003 Circulating hormones and local biotransformation of steroid precursors are both sources of estrogen in human mammary tissue. Estrone-3-sulfate (E(1)S) is an important estrogenic form in premenopausal women, and dehydroepiandrosterone sulfate (DHEAS ...
Pizzagalli, F. +5 more
core +1 more source
Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids [PDF]
Proceedings of the National Academy of Sciences, 1998 The observation was made that dehydroepiandrosterone (DHEA), as the unconjugated steroid, and its sulfate ester (DHEAS) are present in the brain of adult male rats (1). This finding was unforeseen because the rodent steroidogenic glands, including the adrenals, do not secrete significant amounts of DHEA (2).
E E, Baulieu, P, Robel
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Dehydroepiandrosterone sulfate in the assessment of the hypothalamic-pituitary-adrenal axis [PDF]
, 2008 The role of dehydroepiandrosterone-sulfate (DHEA-S) in assessing the integrity of the hypothalamic-pituitary-adrenal (HPA) axis in patients with suspected insufficiency is ...
Allemann, Sabin +6 more
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The association between skeletal maturation and adrenal androgen levels in obese children and adolescents [PDF]
Annals of Pediatric Endocrinology & Metabolism, 2017 PurposeThis study aimed to investigate the association between skeletal maturation and adrenal androgen levels in obese children and adolescents.MethodsFifty-three children and adolescents (aged 7–15 years) diagnosed as obese or overweight were ...
Sung Eun Kim +8 more
doaj +1 more source
The important roles of steroid sulfatase and sulfotransferases in gynecological diseases
Frontiers in Pharmacology, 2016 Gynecological diseases such as endometriosis, adenomyosis and uterine fibroids, and gynecological cancers including endometrial cancer and ovarian cancer, affect a large proportion of women.
Tea eLanisnik Rizner
doaj +1 more source
Neuroactive steroids in depression and anxiety disorders: Clinical studies [PDF]
, 2006 Certain neuroactive steroids modulate ligand-gated ion channels via non-genomic mechanisms. Especially 3 alpha-reduced pregnane steroids are potent positive allosteric modulators of the gamma-aminobutyric acid type A (GABA(A)) receptor.
Eser, Daniela +9 more
core +1 more source
Hypoxia and dehydroepiandrosterone in old age: a mouse survival study
Respiratory Research, 2006 Background Survival remains an issue in pulmonary hypertension, a chronic disorder that often affects aged human adults. In young adult mice and rats, chronic 50% hypoxia (11% FIO2 or 0.5 atm) induces pulmonary hypertension without threatening life.
Quillard Janine +2 more
doaj +1 more source
Journal of Lipid Research, 2015 Steroids are primarily present in human fluids in their sulfated forms. Profiling of these compounds is important from both diagnostic and physiological points of view.
Alberto Sánchez-Guijo +4 more
doaj +1 more source