Dehydroepiandrosterone (DHEA) and its sulfate (DHEAS) are important estrogen precursors, secreted mainly by the adrenal cortex. At late gestation, both DHEA and DHEAS (DHEA(S)) are produced at high concentrations in some species due to the developing ...
Emilee N. Hart +2 more
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Beyond Glucocorticoids: Integrating Dehydroepiandrosterone (DHEA) into Animal Welfare Research
Animal welfare researchers are committed to identifying novel measures for enhancing the quality of life of individual animals. Recently, welfare scientists have emphasized the need for tracking multiple indicators of an animal’s behavioral, emotional ...
Jessica C. Whitham +2 more
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Serum Dehydroepiandrosterone, Dehydroepiandrosterone Sulfate, and Pregnenolone Sulfate Concentrations in Patients with Hyperthyroidism and Hypothyroidism [PDF]
AbstractBackground: Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEA-S) have been suggested to have protective effects against cardiovascular disease, cancer, immune-modulated diseases, and aging. We examined serum concentrations of DHEA, DHEA-S, and pregnenolone sulfate (PREG-S) in patients with thyroid dysfunction.Methods ...
N, Tagawa +8 more
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Dissociation of Serum Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate in Septic Shock [PDF]
Dehydroepiandrosterone (DHEA) replacement in sepsis has been advocated because of the sepsis-associated decrease in serum DHEA sulfate (DHEAS). However, experimental sepsis in rodents leads to down-regulation of DHEA sulfotransferase, which inactivates DHEA to DHEAS, theoretically resulting in higher DHEA levels.The objective of the study was to test ...
Wiebke, Arlt +7 more
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Dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) as neuroactive neurosteroids [PDF]
The observation was made that dehydroepiandrosterone (DHEA), as the unconjugated steroid, and its sulfate ester (DHEAS) are present in the brain of adult male rats (1). This finding was unforeseen because the rodent steroidogenic glands, including the adrenals, do not secrete significant amounts of DHEA (2).
E E, Baulieu, P, Robel
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"Maternal serum Dehydroepiandrosterone Sulfate levels and successful labor induction " [PDF]
To evaluate the maternal serum dehydroepiandrosterone sulfate level as a factor associated with the outcome of labor induction. Venous blood was collected from 45 women at the initiation of labor induction.
Modares Gilani M, Paykari N
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The association between skeletal maturation and adrenal androgen levels in obese children and adolescents [PDF]
PurposeThis study aimed to investigate the association between skeletal maturation and adrenal androgen levels in obese children and adolescents.MethodsFifty-three children and adolescents (aged 7–15 years) diagnosed as obese or overweight were ...
Sung Eun Kim +8 more
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The important roles of steroid sulfatase and sulfotransferases in gynecological diseases
Gynecological diseases such as endometriosis, adenomyosis and uterine fibroids, and gynecological cancers including endometrial cancer and ovarian cancer, affect a large proportion of women.
Tea eLanisnik Rizner
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Dehydroepiandrosterone, Its Sulfate and Cognitive Functions [PDF]
To present a review of cross-sectional and longitudinal studies that investigate the relationship between the hormones Dehydroepiandrosterone (DHEA) and Dehydroepiandrosterone sulfate (DHEA-S) and cognition. Methods: The cognition items included in this review were global cognitive function, memory, attention, executive function, intelligence ...
De Menezes, Karina Junqueira +5 more
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Dehydroepiandrosterone Sulfate Reduces Acoustic Injury of the Guinea-Pig Cochlea
The present study was performed to determine effects of dehydroepiandrosterone sulfate (DHEAS), a neurosteroid, on acoustic injury. Albino guinea pigs were exposed to a 2 kHz pure tone of 120 or 125 dB sound pressure level for 10 min immediately after ...
Keiji Tabuchi +6 more
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