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Is There a Receptor for Dehydroepiandrosterone or Dehydroepiandrosterone Sulfate?
Seminars in Reproductive Medicine, 2004It remains unknown whether dehydroepiandrosterone (DHEA) and DHEA sulfate (DHEAS) have a physiological role other than serving as metabolic intermediates in androgen synthesis. Apart from intracellular metabolism, there is no convincing cellular mechanism of action for physiological concentrations of DHEA(S). Unlike other major steroids, a receptor for
Joseph Dillon
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Dehydroepiandrosterone and Dehydroepiandrosterone Sulfate Dynamics in Obesity
Canadian Journal of Biochemistry, 1975Dehydroepiandrosterone (D) and dehydroepiandrosterone sulfate (DS) dynamics were studied in three obese female subjects following a single injection of [4-14C]D and [7α-3H]-DS tracers. Dynamic parameters were calculated simultaneously by both the urinary and blood method of compartmentalization. Estimates for the urinary secretion and production rates
T, Fehér, L, Halmy
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Importance of dehydroepiandrosterone and dehydroepiandrosterone sulfate in different diseases
Orvosi Hetilap, 2007A dehidroepiandroszteron és szulfatált származéka androgén és ösztrogén hormonok előanyaga, a gonádok szexuálszteroid termeléséhez járul hozzá. A dehidroepiandroszteron-szulfát csak deszulfatálódása után képes részt venni a folyamatban. A harmadik dekádtól kezdve a szérumszintjük fokozatosan csökken, idősebb korban a maximális érték csupán 10–20%-a. Az
Krisztián, Bácsi +6 more
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Testosterone, Dehydroepiandrosterone, and Dehydroepiandrosterone Sulfate in Hyperandrogenic Women
The Journal of Clinical Endocrinology & Metabolism, 1984Serum levels of testosterone (T), dehydroepiandrosterone (DHEA), and DHEA sulfate (DHEA-S) were measured in a group of 285 women with clinical signs of hyperandrogenism (hirsutism and/or acne). Levels of T were elevated in 75.8% of the patients, DHEA in 57.5%, and DHEA-S in 20%. Normal levels of all 3 androgens were found in 13.3%.
E, Steinberger +2 more
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Dehydroepiandrosterone sulfate and dehydroepiandrosterone: neuroactive neurosteroids
Current Opinion in Endocrinology & Diabetes, 2000During the last five years, advances have been made in understanding of the role of dehydroepiandrosterone sulfate (DHEAS) and dehydroepiandrosterone (DHEA) in the central nervous system (CNS). It has become clear that the two molecules can be qualified as neurosteroids and neuroactive steroids.
Yvette Akwa, Etienne-Emile Baulieu
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Dehydroepiandrosterone sulfate and postmenopausal women
Current Opinion in Endocrinology, Diabetes & Obesity, 2011Levels of dehydroepiandrosterone (DHEA) are known to decline with age. In an era of increasing use of supplements to better life, the benefits of DHEA in the aging female population are controversial. The goal of this article is to critically review published studies to determine if there is a role for DHEA supplementation in postmenopausal women.Daily
Rachna M, Goel, Anne R, Cappola
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Dehydroepiandrosterone and Dehydroepiandrosterone-Sulfate and Emotional Processing
2018Steroid hormones are important regulators of brain development, physiological function, and behavior. Among them, dehydroepiandrosterone (DHEA) and dehydroepiandrosterone-sulfate (DHEAS) also do modulate emotional processing and may have mood enhancement effects.
do Vale S, Escera C
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