Results 101 to 110 of about 1,128,553 (311)

Controlled biotechnological production of polyhydroxyalkanoates [PDF]

, 2012
Předložená diplomová práce se zabývá produkcí polyhydroxyalkanoátů (PHA) bakterií Cupriavidus necator H16. Cílem práce byla příprava, selekce a charakterizace mutantních kmenů schopných vyšší produkce PHA.
Šnajdar, Ondřej
core  

Functional responses of methanogenic archaea to syntrophic growth. [PDF]

, 2012
Methanococcus maripaludis grown syntrophically with Desulfovibrio vulgaris was compared with M. maripaludis monocultures grown under hydrogen limitation using transcriptional, proteomic and metabolite analyses.
Arkin, Adam P, Baidoo, Edward E, He, Zhili, Hendrickson, Erik L, Joachimiak, Marcin P, Keasling, Jay D, Leigh, John A, Mukhopadhyay, Aindrila, Rajeev, Lara, Redding-Johanson, Alyssa M, Stahl, David A, Stolyar, Sergey, Walker, Christopher B, Zhou, Jizhong   +13 more
core   +2 more sources

KLK7 overexpression promotes an aggressive phenotype and facilitates peritoneal dissemination in colorectal cancer cells

FEBS Open Bio, EarlyView.
KLK7, a tissue kallikrein‐related peptidase, is elevated in advanced colorectal cancer and associated with shorter survival. High KLK7 levels in ascites correlate with peritoneal metastasis. In mice, KLK7 overexpression increases metastasis. In vitro, KLK7 enhances cancer cell proliferation, migration, adhesion, and spheroid formation, driving ...
Yosr Z. Haffani, Tobias Dreyer, Meriem Naim, Rea Lo Dico, Natalia A. Ignatenko, Viktor Magdolen, Dalila Darmoul   +6 more
wiley   +1 more source

Evolução de CO2 e atividades enzimáticas em amostras de solo tratado com herbicidas CO2 evolution and enzymatic activites in herbicide-treated soil samples

Planta Daninha, 2009
Os efeitos dos herbicidas bentazon, metolachlor, trifluralin, imazethapyr, imazethapyr+lactofen, haloxyfop-methyl, glyphosate e chlorimuron-ethyl, testados em duas concentrações (duas e dez vezes a dose média recomendada por hectare), sobre a atividade ...
G. Fernandez, R.A. Pitelli, M. Cadenazzi
doaj   +1 more source

Succinate dehydrogenase (SDH)-deficient renal carcinoma:a morphologically distinct entity: a clinicopathologic series of 36 tumors from 27 patients [PDF]

, 2014
Succinate dehydrogenase (SDH)-deficient renal carcinoma has been accepted as a provisional entity in the 2013 International Society of Urological Pathology Vancouver Classification.
Belinsky, Cascon, Cascon, Chou, Dwight, Dwight, Eng, Fairchild, Fishbein, Fleming, Gaal, Gill, Gill, Gill, Gill, Gill, Gill, Gill, Gill, Gimm, Henderson, Housley, Janeway, Jasperson, Korpershoek, Malinoc, Miettinen, Miettinen, Miettinen, Neumann, Ni, Oudijk, Paik, Papathomas, Ricketts, Ricketts, Said-Al-Naief, Schimke, Solis, Srigley, Srirangalingam, Srirangalingam, van Nederveen, van Nederveen, Vanharanta, Wagner, Xekouki   +46 more
core   +4 more sources

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

Ammonia assimilation in Bacillus polymyxa. 15N NMR and enzymatic studies [PDF]

, 1987
Pathways of ammonia assimilation into glutamic acid and alanine in Bacillus polymyxa were investigated by 15N NMR spectroscopy in combination with measurements of the specific activities of glutamate dehydrogenase, glutamine synthetase, glutamate ...
Kanamori, Keiko, Roberts, John D., Weiss, Richard L.   +2 more
core  

BACE1 activity impairs neuronal glucose oxidation:rescue by beta-hydroxybutyrate and lipoic acid [PDF]

, 2015
Glucose hypometabolism and impaired mitochondrial function in neurons have been suggested to play early and perhaps causative roles in Alzheimer's disease (AD) pathogenesis. Activity of the aspartic acid protease, beta-site amyloid precursor protein (APP)
Arsenian, Bateman, Beal, Bielarczyk, Blass, Bogaert, Bosetti, Bouzier-Sore, Bubber, Butterworth, Casley, Casley, Caspersen, Coleman, Costantini, Danial, David L. Hamilton, DeKosky, DeKosky, Devi, Du, Fang, Forero, Fukumoto, Geula, Gibson, Giménez-Cassina, Guglielmotto, Gómez-Isla, Hager, Hamilton, Harada, Henderson, Henderson, Hirai, Holsinger, Huang, Hussain, Itoh, Jack, Jack, Jack, Jha, John A. Findlay, Johnson, Kankotia, Kawaja, Kim, Knopman, Ko, Korolainen, Lei, Li, Lustbader, Magistretti, Manczak, Martiskainen, Masdeu, Mastrogiacoma, Maurer, McKenna, Meakin, Michael L. J. Ashford, Mirshamsi, Mosconi, Mosconi, Mowrer, Mucke, Mullen, Nelson, Nilsen, Nunomura, O'Connor, Packer, Parker, Patel, Pereira, Perry, Phypers, Puglielli, Reger, Reiman, Sancheti, Shankar, Shearman, Sinha, Small, Sokoloff, Sorbi, Sowell, Swerdlow, Tyler, Vaishnavi, Vassar, Vassar, Velliquette, Vlassenko, von Kienlin, Wilkins, Wischmeyer, Wise, Xun, Yang, Yao, Yao, Zaidan, Zhang, Zhang, Zhao   +108 more
core   +6 more sources

Alcohol‐induced altered glycans in human tracheal epithelial cells promote bacterial adhesion

FEBS Open Bio, EarlyView.
Alcohol induces altered glycans to promote bacteria adhesion. Heavy alcohol drinking is known to increase the risk of bacterial pneumonia. However, the link between alcohol levels and risk of infection remains underexplored. Recently, we found that alcohol induced α2‐6sialo mucin O‐glycans in human tracheobronchial epithelial cells, which mediated the ...
Pi‐Wan Cheng, Souvik Datta, Derrick R. Samuelson   +2 more
wiley   +1 more source