Results 241 to 250 of about 1,210,240 (343)

Asymmetric Synthesis of Atropisomeric Amines via Transaminase‐Catalyzed Dynamic Kinetic Resolution

Advanced Synthesis &Catalysis, EarlyView.
A dynamic kinetic resolution approach is developed for the atroposelective synthesis of heterobiaryl primary amines. Using transaminases and leveraging Lewis acid‐base interactions to induce racemization, a variety of axially chiral primary amines are produced in high yields and enantioselectivities.
Juan M. Coto‐Cid, Patricia Rodríguez‐Salamanca, Christian M. Heckmann, Caroline E. Paul, Joaquín López‐Serrano, Rosario Fernández, José M. Lassaletta, Valentín Hornillos, Gonzalo de Gonzalo   +8 more
wiley   +1 more source

Lactylation Genes LDHA and LDHC Alleviate Osteoarthritis by Reducing Specific B-Cell Expression: Mechanistic Exploration and Experimental Validation. [PDF]

J Cell Mol Med
Di J, Guo Z, Di Y, Chen T, Qin Y, Xing X, Xiang C.   +6 more
europepmc   +1 more source

Integrated Flexible Zwitterionic Electrochemical Sensor Platform for Real‐Time Salivary Glucose Quantification

Advanced Sensor Research, EarlyView.
A flexible electrochemical sensor platform can enable continuous, real‐time monitoring of salivary glucose for applications confined to spaces such as the oral cavity. Surface modifications with Prussian blue, chitosan, and zwitterionic polymers enhance sensitivity, selectivity, and antiadherent performance.
Stephanie Klinghammer, Gylxhane Kastrati, Leif Riemenschneider, Michael Geiger‐Hoffmann, Luis Antonio Panes‐Ruiz, Johan Peter Woelber, Christian Hannig, Gianaurelio Cuniberti, Torsten Sterzenbach   +8 more
wiley   +1 more source

Amino acid metabolism of the thermophilic acetogen Thermacetogenium phaeum. [PDF]

PLoS One
Cai Y, Marquardt A, Schleheck D, Müller N.   +3 more
europepmc   +1 more source

CO2 Capture, Utilization, and Storage using Amino Acids

Advanced Sustainable Systems, EarlyView.
Amino acid and amino acid‐based ionic liquids show potential for sustainable CO2 capture, benefiting from reactive NH2 groups and low‐energy regeneration. Their use in solvents, functionalized sorbents, direct air capture, mineralization, and CO2 conversion highlights their versatilty and promise for advacing next‐generation CO2 sequestration ...
Md Sariful Sheikh, Jiajie Sui, Bu Wang, Xudong Wang   +3 more
wiley   +1 more source

Lysine succinylation as a metabolic switch in cardiovascular diseases: Mechanistic insights and therapeutic perspectives. [PDF]

Redox Biol
Mu F, Zhang H, Gong R, Lin R, Zhao M, Tao X, Shang L, Xi M, Zhao J, Wang J.   +9 more
europepmc   +1 more source

Elderly Liver Grafts are More Susceptible to Ischemia‐Reperfusion After Prolonged Cold Ischemia than Grafts from Young Donors—An Ex Vivo Liver Machine Perfusion Analysis in Sprague Dawley Rats

Advanced Therapeutics, EarlyView.
This study investigates how donor age and cold ischemia time influence liver perfusion parameters and injury markers. Older livers are more susceptible to longer ischemia times displaying more tissue damage, and higher expression of oxidative stress and apoptosis‐related proteins than livers with shorter ischemia times.
Leonard Boerger, Kilian A. Walter, Anna S. Pietsch, Linda Gilles, Oliver Klein, Karl H. Hillebrandt, Joseph M. G. V. Gassner, Jasper Iske, Johann Pratschke, Felix Krenzien, Igor M. Sauer, Nathanael Raschzok, Simon Moosburner   +12 more
wiley   +1 more source

Lactate dehydrogenase is an indicator for outcomes of short-term and long-term in septic patients. [PDF]

PLoS One
Zeng Z, Guo C, Tang F, Ding N.
europepmc   +1 more source

Study of serum lactate dehydrogenase and lipid profile in patients with chronic cough

, 2021
Mahesh Basavaraj Madole, Dilip Bhave, Mamatha Mt, Ankur Patel   +3 more
openalex   +1 more source

NARFL Knockout Triggers Ferroptosis‐Driven Vascular Endothelial Dysfunction

Advanced Science, EarlyView.
NARFL is vital for CIA and oxidative stress resistance. NARFL deletion in HPMEC cells, zebrafish, and mice is lethal and rescued by a Ferroptosis inhibitor. NARFL deficiency disrupted its interaction with CIA proteins, decreased aconitase activity, increased IRP1 activity, induced Fe overload, and led to ferroptosis and oxidative stress, resulting in ...
Hui Hu, Jing Luo, Li Yu, Daoxi Qi, Boyu Li, Yating Chen, Chen Wang, Xiaokang Zhang, Wenzheng Guo, Qiyong Lou, Gang Zhai, Yonglin Ruan, Jianfei Huang, Shengchi Shi, Zhan Yin, Fang Zheng   +15 more
wiley   +1 more source