Enantiocomplementary Yarrowia lipolytica Oxidoreductases: Alcohol Dehydrogenase 2 and Short Chain Dehydrogenase/Reductase [PDF]
Enzymes of the non-conventional yeast Yarrowia lipolytica seem to be tailor-made for the conversion of lipophilic substrates. Herein, we cloned and overexpressed the Zn-dependent alcohol dehydrogenase ADH2 from Yarrowia lipolytica in Escherichia coli ...
Gernot Strohmeier +2 more
exaly +5 more sources
Screening of Microorganisms Producing Cold-Active Oxidoreductases to Be Applied in Enantioselective Alcohol Oxidation. An Antarctic Survey [PDF]
Several microorganisms were isolated from soil/sediment samples of Antarctic Peninsula. The enrichment technique using (RS)-1-(phenyl)ethanol as a carbon source allowed us to isolate 232 psychrophile/psychrotroph microorganisms.
Leandro Helgueira Andrade +1 more
exaly +5 more sources
Iron-Containing Alcohol Dehydrogenase from Hyperthermophiles [PDF]
Iron-containing alcohol dehydrogenases (Fe-ADHs) from hyperthermophiles represent a distinct class of oxidoreductases characterized by exceptional thermostability, catalytic versatility, and unique metal-dependent properties.
Ching Tse, Kesen Ma
doaj +2 more sources
NAD(P)<sup>+</sup>-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite. [PDF]
Cannabidiol (CBD) undergoes oxidation to 7-hydroxy-CBD in the liver via cytochrome P450 enzymes. 7-Hydroxy-CBD can be further oxidized to 7-carboxy-CBD, the principal circulating metabolite in humans. An aldehyde intermediate, 7-formyl-CBD, is hypothesized to be the precursor of 7-carboxy-CBD; however, the formation of 7-formyl-CBD and the enzymes ...
Wu Q +4 more
europepmc +3 more sources
Engineering a newly identified alcohol dehydrogenase from Sphingobium Sp. for efficient utilization of nicotinamide cofactors biomimetics [PDF]
Nicotinamide cofactor biomimetics (NCBs) serve as low-cost alternatives to the expensive NAD(P)+/NAD(P)H, holding significant potential for applications in oxidoreductases. In this study, an alcohol dehydrogenase (SpADH2) from Sphingobium sp.
Yichun Zhu +5 more
doaj +2 more sources
Biofuel Cells Based on Oxidoreductases and Electroactive Nanomaterials: Development and Characterization [PDF]
Amperometric biosensors (ABSs) and enzymatic biofuel cells (BFCs) share several fundamental principles in their functionality, despite serving different primary purposes.
Olha Demkiv +5 more
doaj +2 more sources
Expanding the Application Range of Microbial Oxidoreductases by an Alcohol Dehydrogenase from Comamonas testosteroni with a Broad Substrate Spectrum and pH Profile [PDF]
Alcohol dehydrogenases catalyse the conversion of a large variety of ketone substrates to the corresponding chiral products. Due to their high regio- and stereospecificity, they are key components in a wide range of industrial applications. A novel alcohol dehydrogenase from Comamonas testosteroni (CtADH) was identified in silico, recombinantly ...
Daniel Bakonyi +2 more
exaly +4 more sources
Factsheet: Alcohol, crime and disorder in the night-time economy [PDF]
The rapid expansion in recent years of the night-time economy (NTE) - now an important part of the leisure, tourism and service industries - raises serious crime and public health ...
Alcohol Concern +2 more
core +4 more sources
Generation of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity [PDF]
AbstractThe l‐lysine‐ϵ‐dehydrogenase (LysEDH) from Geobacillus stearothermophilus naturally catalyzes the oxidative deamination of the ϵ‐amino group of l‐lysine. We previously engineered this enzyme to create amine dehydrogenase (AmDH) variants that possess a new hydrophobic cavity in their active site such that aromatic ketones can bind and be ...
Vasilis Tseliou +4 more
openaire +4 more sources
Roles of Alcohol in Intimate Partner Abuse
There is little available evidence relating to the measurement of alcohol use in IPV relationships (McMurran & Gilchrist, 2008). This mixed-method, multi-phase project aimed to unpick some of the complicated roles that alcohol appears to have in intimate
Laxton, T. +5 more
core +6 more sources

