Results 11 to 20 of about 650,959 (208)

Engineering a newly identified alcohol dehydrogenase from Sphingobium Sp. for efficient utilization of nicotinamide cofactors biomimetics [PDF]

Bioresources and Bioprocessing
Nicotinamide cofactor biomimetics (NCBs) serve as low-cost alternatives to the expensive NAD(P)+/NAD(P)H, holding significant potential for applications in oxidoreductases. In this study, an alcohol dehydrogenase (SpADH2) from Sphingobium sp.
Yichun Zhu, Jieyu Zhou, Xiangyuan Gu, Huiru Wang, Hao Han, Ye Ni   +5 more
doaj   +2 more sources

Biofuel Cells Based on Oxidoreductases and Electroactive Nanomaterials: Development and Characterization [PDF]

Biosensors
Amperometric biosensors (ABSs) and enzymatic biofuel cells (BFCs) share several fundamental principles in their functionality, despite serving different primary purposes.
Olha Demkiv, Nataliya Stasyuk, Galina Gayda, Oksana Zakalska, Mykhailo Gonchar, Marina Nisnevitch   +5 more
doaj   +2 more sources

NAD(P)⁺-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite. [PDF]

Arch Toxicol
Cannabidiol (CBD) undergoes oxidation to 7-hydroxy-CBD in the liver via cytochrome P450 enzymes. 7-Hydroxy-CBD can be further oxidized to 7-carboxy-CBD, the principal circulating metabolite in humans. An aldehyde intermediate, 7-formyl-CBD, is hypothesized to be the precursor of 7-carboxy-CBD; however, the formation of 7-formyl-CBD and the enzymes ...
Wu Q, Fang JL, Nagumalli SK, Guo X, Beland FA.   +4 more
europepmc   +3 more sources

Generation of Oxidoreductases with Dual Alcohol Dehydrogenase and Amine Dehydrogenase Activity [PDF]

Chemistry – A European Journal, 2020
AbstractThe l‐lysine‐ϵ‐dehydrogenase (LysEDH) from Geobacillus stearothermophilus naturally catalyzes the oxidative deamination of the ϵ‐amino group of l‐lysine. We previously engineered this enzyme to create amine dehydrogenase (AmDH) variants that possess a new hydrophobic cavity in their active site such that aromatic ketones can bind and be ...
Vasilis Tseliou, Don Schilder, Marcelo F. Masman, Tanja Knaus, Francesco G. Mutti   +4 more
openaire   +4 more sources

Display of Bombyx mori alcohol dehydrogenases on the Bacillus subtilis spore surface to enhance enzymatic activity under adverse conditions. [PDF]

PLoS ONE, 2011
Alcohol dehydrogenases (ADHs) are oxidoreductases catalyzing the reversible oxidation of alcohols to corresponding aldehydes or ketones accompanied by nicotinamide adenine dinucleotide (NAD) or nicotinamide adenine dinucleotide phosphate (NADP) as ...
Nan Wang, Cheng Chang, Qin Yao, Guohui Li, Lvgao Qin, Liang Chen, Keping Chen   +6 more
doaj   +1 more source

The secretome of Agaricus bisporus: Temporal dynamics of plant polysaccharides and lignin degradation

iScience, 2023
Summary: Despite substantial lignocellulose conversion during mycelial growth, previous transcriptome and proteome studies have not yet revealed how secretomes from the edible mushroom Agaricus bisporus develop and whether they modify lignin models in ...
Katharina Duran, Joris Magnin, Antoine H.P. America, Mao Peng, Roelant Hilgers, Ronald P. de Vries, Johan J.P. Baars, Willem J.H. van Berkel, Thomas W. Kuyper, Mirjam A. Kabel   +9 more
doaj   +1 more source

Core and auxiliary functions of one-carbon metabolism in Pseudomonas putida exposed by a systems-level analysis of transcriptional and physiological responses

mSystems, 2023
The soil bacterium Pseudomonas putida is a robust biomanufacturing host that assimilates a broad range of substrates while efficiently coping with adverse environmental conditions. P. putida is equipped with functions related to one-carbon (C1) compounds
Justine Turlin, Òscar Puiggené, Stefano Donati, Nicolas T. Wirth, Pablo I. Nikel   +4 more
doaj   +1 more source

Alcohol abuse is associated with enhanced pulmonary and systemic xanthine oxidoreductase activity [PDF]

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2017
Acute respiratory distress syndrome (ARDS) is a common and devastating disorder. Alcohol use disorders (AUDs) increase ARDS risk and worsen outcomes through mechanisms that may include enhancement of pulmonary oxidative stress. Alcohol consumption increases activity of the enzyme xanthine oxidoreductase (XOR) that contributes to production of both ...
Mehdi A, Fini, Jeanette, Gaydos, Alicia, McNally, Vijaya, Karoor, Ellen L, Burnham   +4 more
openaire   +2 more sources

Hypoxia-Induced Aquaporins and Regulation of Redox Homeostasis by a Trans-Plasma Membrane Electron Transport System in Maize Roots

Antioxidants, 2022
In plants, flooding-induced oxygen deficiency causes severe stress, leading to growth reduction and yield loss. It is therefore important to understand the molecular mechanisms for adaptation to hypoxia.
Anne Hofmann, Stefanie Wienkoop, Sabine Lüthje   +2 more
doaj   +1 more source

Steroid Oxidoreductase Activity of Alcohol Dehydrogenases from Horse, Rat, and Human Liver. [PDF]

Acta Chemica Scandinavica, 1975
Alcohol dehydrogenase from horse (isoenzyme SS and ES, but not EE), rat and human liver were found to catalyze the NAD-dependent oxidation of 3beta-hydroxy groups in 5alpha- and 5beta-steroids of the C19, C21, and C24 series. The enzymes from horse and rat liver were more active on 5beta-than on 5alpha-steroids. This difference was most marked with the
Tomas Cronholm, Christina Larsén, Jan Sjövall, Hugo Theorell, Åke Åkeson, Hans Sternerup   +5 more
openaire   +2 more sources