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Microbial Alcohol/Aldehyde Oxidoreductases in Enantioselective Conversions
Microbes have an enormous diversity of alcohol and aldehyde oxidoreductases. A brief overview is given of the types known and of some novel ones discovered recently. Except from the classical, NAD-dependent, alcohol dehydrogenase (the long chain, zinc-containing type, EC 1.1.1.1), these enzymes are unexplored with respect to enantioselectivity.
Arie Geerlof +2 more
exaly +3 more sources
Activities of secreted aryl alcohol quinone oxidoreductases from [i]Pycnoporus cinnabarinus[/i] provide insights into fungal degradation of plant biomass [PDF]
Auxiliary activities family 3 subfamily 2 (AA3_2) from the CAZy database comprises various functions related to ligninolytic enzymes, such as fungal aryl alcohol oxidases (AAO) and glucose oxidases, both of which are flavoenzymes. The recent study of the
Faulds, Craig +13 more
core +7 more sources
10 páginas, 7 figuras, 2 tablas -- PAGS nros. 341-350AAO (aryl-alcohol oxidase) provides H2O2 in fungal degradation of lignin, a process of high biotechnological interest.
Hernández-Ortega, Aitor +11 more
core +5 more sources
Nicotinoprotein Alcohol/Aldehyde Oxidoreductases
Enzymes with tightly bound NAD(P), acting as cofactor, have been described in the past. Well known examples include UDP-galactose 4-epimerase from E. coli (Wilson and Hogness, 1964) and lactate-oxaloacetate transhydrogenase from V. alcalescens (Allen, 1966).
Simon de Vries +2 more
core +4 more sources
NAD(P)<sup>+</sup>-dependent alcohol oxidoreductases oxidize 7-hydroxycannabidiol to a reactive formyl metabolite. [PDF]
Cannabidiol (CBD) undergoes oxidation to 7-hydroxy-CBD in the liver via cytochrome P450 enzymes. 7-Hydroxy-CBD can be further oxidized to 7-carboxy-CBD, the principal circulating metabolite in humans. An aldehyde intermediate, 7-formyl-CBD, is hypothesized to be the precursor of 7-carboxy-CBD; however, the formation of 7-formyl-CBD and the enzymes ...
Wu Q +4 more
europepmc +3 more sources
Summary: Despite substantial lignocellulose conversion during mycelial growth, previous transcriptome and proteome studies have not yet revealed how secretomes from the edible mushroom Agaricus bisporus develop and whether they modify lignin models in ...
Katharina Duran +9 more
doaj +1 more source
The soil bacterium Pseudomonas putida is a robust biomanufacturing host that assimilates a broad range of substrates while efficiently coping with adverse environmental conditions. P. putida is equipped with functions related to one-carbon (C1) compounds
Justine Turlin +4 more
doaj +1 more source
Alcohol abuse is associated with enhanced pulmonary and systemic xanthine oxidoreductase activity [PDF]
Acute respiratory distress syndrome (ARDS) is a common and devastating disorder. Alcohol use disorders (AUDs) increase ARDS risk and worsen outcomes through mechanisms that may include enhancement of pulmonary oxidative stress. Alcohol consumption increases activity of the enzyme xanthine oxidoreductase (XOR) that contributes to production of both ...
Mehdi A, Fini +4 more
openaire +2 more sources
In plants, flooding-induced oxygen deficiency causes severe stress, leading to growth reduction and yield loss. It is therefore important to understand the molecular mechanisms for adaptation to hypoxia.
Anne Hofmann +2 more
doaj +1 more source
Microbial Alcohol, Aldehyde and Formate Ester Oxidoreductases
Formation of alcohols by natural processes takes place in the fermentative breakdown of sugars and the oxidative dissimilation of alkanes. In view of the wide-spreadness of these processes, it is understandable that many microbial species have the capacity to degrade these compounds.
Peter W. van Ophem, Johannis A. Duine
core +3 more sources

