Results 1 to 10 of about 223,197 (235)
CycloZ Improves Hyperglycemia and Lipid Metabolism by Modulating Lysine Acetylation in KK-Ay Mice [PDF]
Diabetes & Metabolism Journal, 2023 Background CycloZ, a combination of cyclo-His-Pro and zinc, has anti-diabetic activity. However, its exact mode of action remains to be elucidated.
Jongsu Jeon +15 more
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Conceptual framework for SARS-CoV-2–related lymphopenia
Advanced Biomedical Research, 2022 The emerging of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) outbreak is associated with high morbidity and mortality rates globally. One of the most prominent characteristics of coronavirus disease-19 (COVID-19) is lymphopenia, which is ...
Ilnaz Rahimmanesh +3 more
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“NAD-capQ” detection and quantitation of NAD caps [PDF]
RNA, 2018 RNA 5′ cap structures comprising the metabolic effector nicotinamide adenine dinucleotide (NAD) have been identified in diverse organisms. Here we report a simple, two-step procedure to detect and quantitate NAD-capped RNA, termed “NAD-capQ.” By use of NAD-capQ we quantitate NAD-capped RNA levels in Escherichia coli, Saccharomyces cerevisiae, and human
Grudzien-Nogalska, Ewa +3 more
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Nicotinamide adenine dinucleotide (NAD+). Formal potential of the NAD+/NAD· couple and NAD· dimerization rate [PDF]
Biochimica et Biophysica Acta (BBA) - Bioenergetics, 1984 The rate constant, kd, for the dimerization of the free radical (NAD), produced on the initial one-electron reduction of NAD+, was measured by double potential-step chronoamperometry, fast-scan cyclic voltammetry (cathodic-anodic peak current ratio) and slow-scan cyclic voltammetry (peak potential shift) for a medium in which neither NAD+ nor its ...
M A, Jensen, P J, Elving
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Mitochondrial dysfunction at the cornerstone of inflammatory exacerbation in aged macrophages
Exploration of Immunology, 2023 Immunosenescence encompasses multiple age-related adaptations that result in increased susceptibility to infections, chronic inflammatory disorders, and higher mortality risk.
Rafael Moura Maurmann +3 more
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Enfermedad del coronavirus (covid-19) y las sirtuinas
Revista de la Facultad de Ciencias Médicas de Córdoba, 2020 Las proteínas desacetilasas dependientes del NAD+, se denominan Sirtuinas (SIRT). Objetivos: estudiar las sirtuinas involucradas en el cáncer, así como los estudios de inhibición de SIRT1 en pacientes con la enfermedad del coronavirus COVID-19 ...
Ronald Eleazar Huarachi Olivera +1 more
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CD38 in Neurodegeneration and Neuroinflammation
Cells, 2020 Neurodegenerative diseases are characterized by neuronal degeneration as well as neuroinflammation. While CD38 is strongly expressed in brain cells including neurons, astrocytes as well as microglial cells, the role played by CD38 in neurodegeneration ...
Serge Guerreiro +3 more
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Medicine Science, 2020 Tuberculosis is an infectious disease, which is caused by the Mycobacterium tuberculosis complex. This disease leads to up to 1.3 million deaths out of more than eight million cases every year.
Selami Gunal +2 more
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Investigation of sand in piping [PDF]
Zbornik Matice Srpske za Prirodne Nauke, 2012 For the investigation of the grain size distribution of the material washed out from the piping, we used 20 samples originating from different places on the Danube and the Tisza rivers.
Nađ Laslo
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Assays for NAD+-Dependent Reactions and NAD+ Metabolites [PDF]
, 2018 Nicotinamide adenine dinucleotide (NAD+) is an essential redox cofactor and signaling molecule that controls the activity of enzymes involved in metabolism, DNA repair, and cellular survival, such as the PARPs, CD38, and the sirtuins. Here, we describe three methods for measuring the activity of these enzymes: the etheno-NAD+ assay measures NAD ...
Michael B, Schultz +3 more
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