The homospermidine synthases from P. aeruginosa and B. viridis, as well as their single‐residue variants, are compared based on crystal structures and activity assays. A high structural similarity is demonstrated, suggesting the equivalent involvement of relevant residues in the reaction mechanism and catalytic dependence on cation–π interaction ...
F. Helfrich, Axel J. Scheidig
wiley +1 more source
The essential schistosome tegumental ectoenzyme SmNPP5 can block NAD-induced T cell apoptosis
Infection with intravascular platyhelminths of the genus Schistosoma can result in the debilitating disease schistosomiasis. Schistosomes (blood flukes) can survive in the host for many years.
Catherine S. Nation +2 more
doaj +1 more source
The evaluation of possibilities of sustainable tourism and recreation in the Mrtva Tisa area near Čurug7 [PDF]
The preserved parts of the nature or areas that are inteded to be protected and well-planned in terms of harmonizing the nature and tourist activities and recreation could become potential eco-tourist attractions.
Nađ Imre
doaj +1 more source
Keeping the balance in NAD metabolism [PDF]
Research over the last few decades has extended our understanding of nicotinamide adenine dinucleotide (NAD) from a vital redox carrier to an important signalling molecule that is involved in the regulation of a multitude of fundamental cellular ...
Van Linden, Magali R +5 more
core +1 more source
SPAAC-NAD-seq, a sensitive and accurate method to profile NAD+-capped transcripts [PDF]
Nicotinamide adenine diphosphate (NAD+) is a novel messenger RNA 5' cap in Escherichia coli, yeast, mammals, and Arabidopsis Transcriptome-wide identification of NAD+-capped RNAs (NAD-RNAs) was accomplished through NAD captureSeq, which combines ...
Xia, Yiji +19 more
core +1 more source
Homogeneous nucleation of NAD and NAT in liquid stratospheric aerosols: insufficient to explain denitrification [PDF]
Knopf DA, Koop T, Luo BP, Weers UG, Peter T. Homogeneous nucleation of NAD and NAT in liquid stratospheric aerosols: insufficient to explain denitrification. ATMOSPHERIC CHEMISTRY AND PHYSICS. 2002;2(3):207-214.The nucleation of NAD and NAT from HNO3/H2O
U. G. Weers +10 more
core +2 more sources
CD38, CD157, and RAGE as Molecular Determinants for Social Behavior
Recent studies provide evidence to support that cluster of differentiation 38 (CD38) and CD157 meaningfully act in the brain as neuroregulators. They primarily affect social behaviors. Social behaviors are impaired in Cd38 and Cd157 knockout mice. Single-
Haruhiro Higashida +22 more
doaj +1 more source
Development of the Cerebrospinal Fluid in Early Stage after Hemorrhage in the Central Nervous System
Extravasation of blood in the central nervous system (CNS) represents a very strong damaged associated molecular patterns (DAMP) which is followed by rapid inflammation and can participate in worse outcome of patients.
Petr Kelbich +10 more
doaj +1 more source
NAD+ Homeostasis and NAD+-Consuming Enzymes: Implications for Vascular Health [PDF]
Nicotinamide adenine dinucleotide (NAD+) is a ubiquitous metabolite that takes part in many key redox reactions. NAD+ biosynthesis and NAD+-consuming enzymes have been attracting markedly increasing interest since they have been demonstrated to be ...
Arianna Vignini, Roberto Campagna
core +1 more source
Need for NAD+: Focus on Striated Muscle Laminopathies
International audienceLaminopathies are a heterogeneous group of rare diseases caused by genetic mutations in the LMNA gene, encoding A-type lamins. A-type lamins are nuclear envelope proteins which associate with B-type lamins to form the nuclear lamina,
Muchir, Antoine +3 more
core +1 more source

