Results 31 to 40 of about 223,197 (235)
Murine iNKT cells are depleted by liver damage via activation of P2RX7
European Journal of Immunology, Volume 50, Issue 10, Page 1515-1524, October 2020., 2020 Drug‐induced liver injury activates a suicide pathway in hepatic iNKT cells. The tissue damage induced release of ATP and NAD into the extracellular space triggers the receptor P2RX7 and leads locally to a long‐lasting depletion of iNKT cells. Abstract Invariant natural killer T cells (iNKT) constitute up to 50% of liver lymphocytes and contribute to ...
Astrid A. Bovens +6 more
wiley +1 more source
Sava Savanović: el primer vampiro serbio y los muertos vivientes de los Balcanes
Balajú, 2016 Este artículo se presenta una breve exposición de las tradiciones culturales en torno a los vampiros en las zonas de Serbia, Ucrania y la Transilvania medieval.
Jelena Nađ
doaj +1 more source
NAD-seq for profiling the NAD+ capped transcriptome of Arabidopsis thaliana
STAR Protocols, 2021 Eukaryotic RNAs can be modified with a non-canonical 5' nicotinamide adenine dinucleotide (NAD+) cap. NAD-seq identifies transcriptome-wide NAD+ capped RNAs. NAD-seq takes advantage of click chemistry to allow the capture of NAD+ capped RNAs. Unlike other approaches, NAD-seq does not require DNA synthesis on beads, but this technique uses full NAD ...
Xiang Yu +2 more
openaire +3 more sources
Grabbing the genome by the NADs [PDF]
Chromosoma, 2015 The regions of the genome that interact frequently with the nucleolus have been termed nucleolar-associated domains (NADs). Deep sequencing and DNA-fluorescence in situ hybridization (FISH) experiments have revealed that these domains are enriched for repetitive elements, regions of the inactive X chromosome (Xi), and several RNA polymerase III ...
Matheson, Timothy D., Kaufman, Paul D.
openaire +3 more sources
Land, 2023 The need to achieve the sustainability goals and to reduce the continuous exploitation of the limited urban areas increases requests for the regeneration of brownfields.
Robert Ato Newton +4 more
doaj +1 more source
The Journal of Physiology, EarlyView.Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga +8 more
wiley +1 more source
Outlook of logging perspectives in the Czech Republic for the period 2013-2032
Journal of Forest Science, 2014 The aim of the submitted work was to analyze the outlook of logging perspectives in the next two decades (2013-2032) for all forests in the territory of the Czech Republic.
M. Synek, J. Vašíček, M. Zeman
doaj +1 more source
Psychomotor activities in the context of kinanthropology: Review
Tělesná Kultura, 2015 BACKGROUND: Any scholar developing a therapeutic method shall be concerned with its historical and theoretical groundings, scientifically verifiedfacts, and information from professional publications.
Běla Hátlová +2 more
doaj +1 more source
Timing of NAD Deficiency During Organogenesis Dictates Defect Type and Penetrance
The FASEB Journal, Volume 40, Issue 3, 15 February 2026.Pregnant mice on a vitamin B3‐free and tryptophan‐limited diet have embryos with Congenital NAD Deficiency Disorder, characterized by malformations and/or death. We longitudinally tracked the maternal NAD metabolome, embryo growth, and malformation occurrence. Mice with lower NAD Salvage Pathway metabolite levels and minimal levels of derived excretion
Kayleigh Bozon +6 more
wiley +1 more source
Clinical and Translational Medicine, Volume 15, Issue 8, August 2025.Loss of intestinal epithelial fucosylation exacerbates alcohol‐related liver injuries. Intestinal epithelial deletion of Fut2 disrupts nicotinamide (NAM) metabolism due to the decline in bacterial nicotinamidase (PncA). Supplemented with pncA overexpressed E.coli to restore gut PncA levels can improve liver damage in alcohol‐induced intestinal ...
Liuying Chen +9 more
wiley +1 more source