Results 51 to 60 of about 223,197 (235)

Can Aspartate Aminotransferase in the Cerebrospinal Fluid Be a Reliable Predictive Parameter?

open access: yesBrain Sciences, 2020
Brain ischemia after central nervous system (CNS) bleeding significantly influences the final outcome of patients. Catalytic activities of aspartate aminotransferase (AST) in the cerebrospinal fluid (CSF) to detect brain ischemia were determined in this ...
Petr Kelbich   +9 more
doaj   +1 more source

Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila

open access: yesAging Cell, Volume 23, Issue 4, April 2024.
Our study explores the impact of kynurenine pathway (KP) modulation and NAD+ supplementation on aging Drosophila. We found that KP inhibition combined with NAD+ precursors significantly enhances physical performance and extends life span. These findings suggest that targeted interventions in KP and NAD+ metabolism can synergistically improve health ...
Mariann M. Gabrawy   +18 more
wiley   +1 more source

Metabolic control of mitophagy

open access: yesEuropean Journal of Clinical Investigation, Volume 54, Issue 4, April 2024.
Abstract Mitochondrial dysfunction is a major hallmark of ageing and related chronic disorders. Controlled removal of damaged mitochondria by the autophagic machinery, a process known as mitophagy, is vital for mitochondrial homeostasis and cell survival.
Andreas Zimmermann   +6 more
wiley   +1 more source

Dynamical analysis of machining tool body with reinforced inner core of circular shape [PDF]

open access: yesApplied and Computational Mechanics, 2009
The vibration analysis of a clamped beam structure representing vibrating machining body tool is solved in this paper. The required modal properties of beam are obtained by application the reinforcing core with circular cross section.
Naď M.
doaj  

Personalized Porous Gelatin Methacryloyl Sustained‐Release Nicotinamide Protects Against Noise‐Induced Hearing Loss

open access: yesAdvanced Science, Volume 11, Issue 12, March 27, 2024.
NAD+ decreases in cochlear after noise trauma, and nicotinamide supplementation boosts NAD+ and prevents neuroexcitatory in cochlear by round window administration. Personalized porous gelatin methacryloyl (PGMA) achieves long term drug release in cochlear, and nicotinamide encapsulated PGMA enhances mitochondria and synapse function, and protects ...
Baoyi Feng   +10 more
wiley   +1 more source

Creativity from Robert Sternberg's perspective [PDF]

open access: yesZbornik Radova Filozofskog Fakulteta u Prištini
This paper aims to present and analyze both theories and models of Robert Sternberg, one of the most prolific and well-cited researchers in the field of creativity.
Nađ Ivona J.
doaj   +1 more source

NAD+ surfaces again [PDF]

open access: yesBiochemical Journal, 2004
NAD+ and its metabolites serve important functions in intracellular signalling. NAD+-mediated regulatory processes also take place on the cell surface, particularly of immune cells. In this issue of the Biochemical Journal, Gerth et al. have demonstrated a new mechanism of Ca2+ uptake into monocytes which is triggered by NAD+ or its degradation product,
Mathias, Ziegler, Marc, Niere
openaire   +2 more sources

Biodistribution and toxicity assessment of methoxyphenyl phosphonium carbosilane dendrimers in 2D and 3D cell cultures of human cancer cells and zebrafish embryos

open access: yesScientific Reports, 2023
The consideration of human and environmental exposure to dendrimers, including cytotoxicity, acute toxicity, and cell and tissue accumulation, is essential due to their significant potential for various biomedical applications.
Zuzana Žmudová   +8 more
doaj   +1 more source

Aerial Bombing Crater Identification: Exploitation of Precise Digital Terrain Models

open access: yesISPRS International Journal of Geo-Information, 2020
Places of past conflicts and persistent objects that reflect such events often attract the attention of archaeological prospection which facilitates the construction of conflict narratives. Field prospection as a precise method for localization of aerial
Martin Dolejš   +3 more
doaj   +1 more source

Eskimi IN in NAD Inuiti [PDF]

open access: yesSlovene Linguistic Studies, 2011
The essay considers the advisability of various names for the Aleut peoples and languages from the perspective of the Slovene language.
openaire   +3 more sources

Home - About - Disclaimer - Privacy