Results 41 to 50 of about 184,095 (185)
Timing of NAD Deficiency During Organogenesis Dictates Defect Type and Penetrance
Pregnant mice on a vitamin B3‐free and tryptophan‐limited diet have embryos with Congenital NAD Deficiency Disorder, characterized by malformations and/or death. We longitudinally tracked the maternal NAD metabolome, embryo growth, and malformation occurrence. Mice with lower NAD Salvage Pathway metabolite levels and minimal levels of derived excretion
Kayleigh Bozon +6 more
wiley +1 more source
AMERICAN MULTI-DWELLING ARCHITECTURE OF THE SECOND HALF OF THE 19TH CENTURY AND FIRST HALF OF THE 20TH CENTURY [PDF]
At the end of the 19th and beginning of the 20th century, the evolution of American multiple-dwelling architecture was marked by the passage from the standard construction of single-family standalone homes and row houses to a new housing typology which ...
Srđan Nađ
doaj
Loss of intestinal epithelial fucosylation exacerbates alcohol‐related liver injuries. Intestinal epithelial deletion of Fut2 disrupts nicotinamide (NAM) metabolism due to the decline in bacterial nicotinamidase (PncA). Supplemented with pncA overexpressed E.coli to restore gut PncA levels can improve liver damage in alcohol‐induced intestinal ...
Liuying Chen +9 more
wiley +1 more source
As fluvial pollution may endanger the quality of water and solids transported by rivers, mapping and evaluation of historically polluted fluvial sediments is an urgent topic.
Jitka Elznicová +5 more
doaj +1 more source
Maternal circulatory L‐tryptophan (TRP) and nicotinamide (NAM) levels are proportional to dietary TRP intake. Yolk sacs, but not embryos, perform NAD de novo synthesis. This study explores the exchange of NAD precursors between mother and conceptus, and NAD generation in conceptal tissues via the NAD de novo synthesis (blue) or salvage (red) pathways ...
Kayleigh Bozon +6 more
wiley +1 more source
Structural dynamic modification of vibrating systems [PDF]
Vibration and acoustic requirements are becoming increasingly important in the design of mechanical structures. The need to vary the structural behaviour to solve noise and vibration problems occurs at design or prototype stage, giving rise to the so ...
Naď M.
doaj
Effects of Aging on Glucose and Lipid Metabolism in Mice
Lien et al. report a characterization of metabolism with aging across three different strains of mice. They find that glucose metabolism is robust during healthy aging; however, aging tissues exhibit evidence of upregulated fatty acid and sphingolipid metabolism reactions that regenerate NAD+ from NADH.
Evan C. Lien +8 more
wiley +1 more source
Can Aspartate Aminotransferase in the Cerebrospinal Fluid Be a Reliable Predictive Parameter?
Brain ischemia after central nervous system (CNS) bleeding significantly influences the final outcome of patients. Catalytic activities of aspartate aminotransferase (AST) in the cerebrospinal fluid (CSF) to detect brain ischemia were determined in this ...
Petr Kelbich +9 more
doaj +1 more source
Corporate Social Responsibility of Organizations as Part of a Quality Management System
The paper deals with the topic of social responsibility in selected organizations in the Czech Republic. This topic is mainly associated with the requirements for economical and ecological production.
Střihavková Elena +2 more
doaj +1 more source
Abstract Purpose This goal of this study was to optimize spectrally selective 1H‐MRS methods for large‐volume acquisition of low‐concentration metabolites with downfield resonances at 7 T and 3 T, with particular attention paid to detection of nicotinamide adenine dinucleotide (NAD+) and tryptophan.
Neil E. Wilson +5 more
wiley +1 more source

