Results 41 to 50 of about 192,695 (172)

Outlook of logging perspectives in the Czech Republic for the period 2013-2032

open access: yesJournal of Forest Science, 2014
The aim of the submitted work was to analyze the outlook of logging perspectives in the next two decades (2013-2032) for all forests in the territory of the Czech Republic.
M. Synek, J. Vašíček, M. Zeman
doaj   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga   +8 more
wiley   +1 more source

Psychomotor activities in the context of kinanthropology: Review

open access: yesTělesná Kultura, 2015
BACKGROUND: Any scholar developing a therapeutic method shall be concerned with its historical and theoretical groundings, scientifically verifiedfacts, and information from professional publications.
Běla Hátlová   +2 more
doaj   +1 more source

The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging

open access: yesAging Cell, Volume 25, Issue 5, May 2026.
We revealed the pathophysiological significance and therapeutic potential of adipocyte mitochondrial NAD transporter, namely solute carrier family 25 member 51 (SLC25A51), in age‐associated metabolic diseases, particularly adipose tissue mitochondrial function, obesity, and insulin resistance, by analyzing adipocyte‐specific Slc25a51 knockout (ASKO ...
Daiki Kojima   +19 more
wiley   +1 more source

NAD+-related dysregulation in asymptomatic phases of ALS: early biomarkers of the disease?

open access: yes
Background: nowadays, there is a lack of effective therapies for Amyotrophic Lateral Sclerosis (ALS). This is largely attributed to late diagnosis and incomplete understanding of the mechanisms determining the disease. Nicotinamide Adenine Dinucleotide
Sara Colombo   +7 more
core   +3 more sources

A combination of ketones and NAD+ precursor preserves white matter integrity in mild cognitive impairment

open access: yesAlzheimer's &Dementia: Translational Research &Clinical Interventions, Volume 12, Issue 2, April/June 2026.
Abstract INTRODUCTION Brain glucose metabolism declines and myelin deteriorates as Alzheimer's disease (AD) develops. Adequate energy supply to white matter (WM) is critical to maintain myelin integrity and axonal function. An exogenous source of ketones bypasses the glucose‑specific brain energy deficit and improves cognitive outcomes in mild ...
Maggie Roy   +16 more
wiley   +1 more source

Tailoring Targeted Therapy to Individual Patients: Lessons to be Learnt from the Development of Mitomycin C [PDF]

open access: yes, 2007
The modern era of targeted therapeutics offers the potential to tailor therapy to individual patients whose tumours express a specific target. Previous attempts to forecast tumour response to conventional chemotherapeutics based on similar principles ...
Phillips, Roger M, Volpato, Milene
core   +3 more sources

Identifying and categorizing influencers on Instagram with eye tracker [PDF]

open access: yesSpanish Journal of Marketing-ESIC
Purpose – This paper aims to explore the recognition and success of different ways of branding native advertising in influencer marketing. Design/methodology/approach – The data are evaluated using statistical tests, correlation and cluster analysis ...
Michaela Jánská   +2 more
doaj   +1 more source

Stopping the Mobile Robotic Vehicle at a Defined Distance from the Obstacle by Means of an Infrared Distance Sensor

open access: yesSensors, 2021
The article deals with the creation of a program for stopping an autonomous robotic vehicle Robotino® 4. generation at a defined distance from an obstacle. One of the nine infrared distance sensors located on the frame of the robotic vehicle in the front
Frantisek Klimenda   +3 more
doaj   +1 more source

Timing of NAD Deficiency During Organogenesis Dictates Defect Type and Penetrance

open access: yesThe FASEB Journal, Volume 40, Issue 3, 15 February 2026.
Pregnant mice on a vitamin B3‐free and tryptophan‐limited diet have embryos with Congenital NAD Deficiency Disorder, characterized by malformations and/or death. We longitudinally tracked the maternal NAD metabolome, embryo growth, and malformation occurrence. Mice with lower NAD Salvage Pathway metabolite levels and minimal levels of derived excretion
Kayleigh Bozon   +6 more
wiley   +1 more source

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