Results 41 to 50 of about 374,259 (227)

Study on the mechanism of quinolinic phosphoribosyltransferase regulating the biological behaviors of glioma cells

Chinese Journal of Contemporary Neurology and Neurosurgery
Objective To investigate the effects of quinolinic phosphoribosyltransferase (QPRT) on the proliferation, migration and invasion of glioma cells, and to preliminarily elucidate its potential molecular regulatory mechanisms.
QIN Hu, ZHENG Yi-tong, LIU Wen, MAIMAITI Aierpati, LI Ya-bin, WANG Yong-xin   +5 more
doaj   +1 more source

Structural dynamic modification of circular disc using pre-stressed fields

Research in Agricultural Engineering, 2005
Dynamical properties of circular discs are investigated in this paper. One of the techniques of the disc modifications to achieve the required dynamic properties is to initiate pre-stress in disc plane.
M. Naď
doaj   +1 more source

Badać – nie wykluczając Rozważania nad „metodologią dostępności” [PDF]

, 2020
W artykule „Badać – nie wykluczając. Rozważania nad metodologią dostępności” autorka podejmuje kwestie związane z praktyczną organizacją badań osób z różnymi niepełnosprawnościami.
Sztobryn-Giercuszkiewicz, Joanna, Joanna Sztobryn-Giercuszkiewicz   +1 more
core   +1 more source

sj-docx-3-nad-10.1177_14550725221143180 - Supplemental material for Overdosevarslingssystemer – en kartleggingsoversikt med maskinlæring

, 2023
Supplemental material, sj-docx-3-nad-10.1177_14550725221143180 for Overdosevarslingssystemer – en kartleggingsoversikt med maskinlæring by Tiril C. Borge and Ashley E.
Tiril C. Borge (15217337), Ashley E. Muller (16944055)   +1 more
core   +1 more source

Nicotinic Acid Restriction Enhances the Therapeutic Benefit of NAMPT Inhibition in Small‐Cell Lung Cancer Models

Cancer Science, EarlyView.
Dietary NA restriction converts the effect of NAMPT inhibition from cytostatic to cytotoxic in SCLC in vivo. ABSTRACT Small‐cell lung cancer (SCLC) is an aggressive malignancy with limited therapeutic options. We previously showed that nicotinic acid riboside (NAR) sustains NAD biosynthesis in vivo and compensates for NAMPT inhibition in SCLC models ...
Kyoji Tsurumi, Miyuki Nomura, Mai Ouchi, Shigehiro Yagishita, Naohiko Kikuchi, Taku Sato, Mami Morita, Yoji Yamashita, Kayoko Hayashi, Tomoyoshi Soga, Akinobu Hamada, Tatsuro Fukuhara, Nobuhiro Tanuma   +12 more
wiley   +1 more source

NAD replenishment restores mitochondrial function and thermogenesis in the brown adipose tissue of mice with obesity

The Journal of Physiology, EarlyView.
Abstract figure legend A high‐fat diet (HFD) induces brown adipose tissue (BAT) whitening, mitochondrial dysfunction (damaged cristae, fragmentation), reduced NAD+ levels and impaired thermogenesis, leading to lower energy expenditure and metabolic inflexibility.
Renata R. Braga, Matheus B. Rocha, Ana P. Morelli, Raul G. da Costa, Marcelo A. S. Mori, Adelino S. R. da Silva, José R. Pauli, Dennys E. Cintra, Eduardo R. Ropelle   +8 more
wiley   +1 more source

Cooperation between subcellular NAD pools in the maintenance of NAD-dependent processes [PDF]

, 2018
Nicotinamide adenine dinucleotide (NAD) is needed as a cofactor in several processes throughout the cell, and its availability is decisive for the activity of many NAD-dependent enzymes.
Tolås, Ingvill
core  

State of Brownfields in the Northern Bohemia, Saxony and Lower Silesian Regions and Prospects for Regeneration by Utilization of the Phytotechnology with the Second Generation Crops

Land, 2023
The need to achieve the sustainability goals and to reduce the continuous exploitation of the limited urban areas increases requests for the regeneration of brownfields.
Robert Ato Newton, Valentina Pidlisnyuk, Eliška Wildová, Ludmila Nováková, Josef Trögl   +4 more
doaj   +1 more source

The Mitochondrial NAD Transporter SLC25A51 in Adipocytes Regulates Adipose Tissue Mitochondrial Function and Systemic Metabolism During Aging

Aging Cell, Volume 25, Issue 5, May 2026.
We revealed the pathophysiological significance and therapeutic potential of adipocyte mitochondrial NAD transporter, namely solute carrier family 25 member 51 (SLC25A51), in age‐associated metabolic diseases, particularly adipose tissue mitochondrial function, obesity, and insulin resistance, by analyzing adipocyte‐specific Slc25a51 knockout (ASKO ...
Daiki Kojima, Keisuke Yaku, Shotaro Kosugi, Ryunosuke Mitsuno, Kenji Kaneko, Yoshinaga Kawano, Akihito Hishikawa, Seiya Mizuno, Manami Katoh, Akiko Satoh, Shinya Toyokuni, Tatsuhiko Azegami, Kenichiro Kinouchi, Shintaro Yamaguchi, Hiroshi Itoh, Takeshi Kanda, Toshimasa Yamauchi, Takashi Nakagawa, Kaori Hayashi, Jun Yoshino   +19 more
wiley   +1 more source

Outlook of logging perspectives in the Czech Republic for the period 2013-2032

Journal of Forest Science, 2014
The aim of the submitted work was to analyze the outlook of logging perspectives in the next two decades (2013-2032) for all forests in the territory of the Czech Republic.
M. Synek, J. Vašíček, M. Zeman
doaj   +1 more source