Results 61 to 70 of about 964,195 (224)

Threat of Pollution Hotspots Reworking in River Systems: Case Study of the Ploučnice River (Czech Republic)

open access: yesISPRS International Journal of Geo-Information, 2019
As fluvial pollution may endanger the quality of water and solids transported by rivers, mapping and evaluation of historically polluted fluvial sediments is an urgent topic.
Jitka Elznicová   +5 more
doaj   +1 more source

Analysis of ligation and DNA binding by Escherichia coli DNA ligase (LigA). [PDF]

open access: yes, 2005
NAD+-dependent DNA ligases are essential enzymes in bacteria, with the most widely studied of this class of enzymes being LigA from Escherichia coli. NAD+-dependent DNA ligases comprise several discrete structural domains, including a BRCT domain at the ...
Adam Wilkinson   +59 more
core   +1 more source

Optimization of 1H‐MRS methods for large‐volume acquisition of low‐concentration downfield resonances at 3 T and 7 T

open access: yesMagnetic Resonance in Medicine, Volume 93, Issue 1, Page 18-30, January 2025.
Abstract Purpose This goal of this study was to optimize spectrally selective 1H‐MRS methods for large‐volume acquisition of low‐concentration metabolites with downfield resonances at 7 T and 3 T, with particular attention paid to detection of nicotinamide adenine dinucleotide (NAD+) and tryptophan.
Neil E. Wilson   +5 more
wiley   +1 more source

Corporate Social Responsibility of Organizations as Part of a Quality Management System

open access: yesProduction Engineering Archives, 2021
The paper deals with the topic of social responsibility in selected organizations in the Czech Republic. This topic is mainly associated with the requirements for economical and ecological production.
Střihavková Elena   +2 more
doaj   +1 more source

Impurity effect on low-temperature polarisation of the charge-density-waves in o-TaS$_3$

open access: yes, 1998
The temperature dependence of the low-temperature dielectric response is studied in o-TaS$_3$ samples doped by Nb, Se, and Ni and for nominally pure ones.
Baklanov   +21 more
core   +1 more source

Effect of Dietary Ketosis and Nicotinamide Riboside on Hippocampal Krebs Cycle Intermediates and Mitochondrial Energetics in a DNA Repair‐Deficient 3xTg/POLβ+/− Alzheimer Disease Mouse Model

open access: yesJournal of Neurochemistry, Volume 169, Issue 1, January 2025.
Alzheimer disease causes neurodegeneration of the hippocampus. It impedes brain glucose metabolism and impairs mitochondrial energy along electron transport chain (ETC). Will a ketone‐based diet with nicotinamide riboside restore hippocampal energy in an Alzheimer mouse model?
Robert Pawlosky   +5 more
wiley   +1 more source

Can Aspartate Aminotransferase in the Cerebrospinal Fluid Be a Reliable Predictive Parameter?

open access: yesBrain Sciences, 2020
Brain ischemia after central nervous system (CNS) bleeding significantly influences the final outcome of patients. Catalytic activities of aspartate aminotransferase (AST) in the cerebrospinal fluid (CSF) to detect brain ischemia were determined in this ...
Petr Kelbich   +9 more
doaj   +1 more source

A Subtlety of the Schr\"{o}dinger Picture Dynamics

open access: yes, 2005
We address a mathematical and physical status of exotic (like e.g. fractal) wave packets and their quantum dynamics. To this end, we extend the formal meaning of the Schr\"{o}dinger equation beyond the domain of the Hamiltonian.
Akhiezer   +12 more
core   +3 more sources

Effects of niacin restriction on sirtuin and PARP responses to photodamage in human skin. [PDF]

open access: yes, 2012
Sirtuins (SIRTs) and poly(ADP-ribose) polymerases (PARPs), NAD(+)-dependent enzymes, link cellular energy status with responses to environmental stresses.
Benavente, Claudia A   +2 more
core   +3 more sources

Dual treatment with kynurenine pathway inhibitors and NAD+ precursors synergistically extends life span in Drosophila

open access: yesAging Cell, Volume 23, Issue 4, April 2024.
Our study explores the impact of kynurenine pathway (KP) modulation and NAD+ supplementation on aging Drosophila. We found that KP inhibition combined with NAD+ precursors significantly enhances physical performance and extends life span. These findings suggest that targeted interventions in KP and NAD+ metabolism can synergistically improve health ...
Mariann M. Gabrawy   +18 more
wiley   +1 more source

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