Results 71 to 80 of about 374,259 (227)
Corporate Social Responsibility of Organizations as Part of a Quality Management System
Production Engineering Archives, 2021 The paper deals with the topic of social responsibility in selected organizations in the Czech Republic. This topic is mainly associated with the requirements for economical and ecological production.
Střihavková Elena +2 more
doaj +1 more source
Journal of Neurochemistry, Volume 169, Issue 1, January 2025.Alzheimer disease causes neurodegeneration of the hippocampus. It impedes brain glucose metabolism and impairs mitochondrial energy along electron transport chain (ETC). Will a ketone‐based diet with nicotinamide riboside restore hippocampal energy in an Alzheimer mouse model?
Robert Pawlosky +5 more
wiley +1 more source
Aging Cell, Volume 23, Issue 4, April 2024.Our study explores the impact of kynurenine pathway (KP) modulation and NAD+ supplementation on aging Drosophila. We found that KP inhibition combined with NAD+ precursors significantly enhances physical performance and extends life span. These findings suggest that targeted interventions in KP and NAD+ metabolism can synergistically improve health ...
Mariann M. Gabrawy +18 more
wiley +1 more source
Metabolic control of mitophagy
European Journal of Clinical Investigation, Volume 54, Issue 4, April 2024.Abstract Mitochondrial dysfunction is a major hallmark of ageing and related chronic disorders. Controlled removal of damaged mitochondria by the autophagic machinery, a process known as mitophagy, is vital for mitochondrial homeostasis and cell survival.
Andreas Zimmermann +6 more
wiley +1 more source
, 2023 Dietary vitamin B3 components, such as nicotinamide and nicotinic acid, are precursors to the ubiquitous redox cofactor nicotinamide adenine dinucleotide (NAD+). NAD+ levels are thought to decline with age and disease.
Marie E. Migaud +2 more
core +1 more source
Dynamical analysis of machining tool body with reinforced inner core of circular shape [PDF]
Applied and Computational Mechanics, 2009 The vibration analysis of a clamped beam structure representing vibrating machining body tool is solved in this paper. The required modal properties of beam are obtained by application the reinforcing core with circular cross section.
Naď M.
doaj
Advanced Science, Volume 11, Issue 12, March 27, 2024.NAD+ decreases in cochlear after noise trauma, and nicotinamide supplementation boosts NAD+ and prevents neuroexcitatory in cochlear by round window administration. Personalized porous gelatin methacryloyl (PGMA) achieves long term drug release in cochlear, and nicotinamide encapsulated PGMA enhances mitochondria and synapse function, and protects ...
Baoyi Feng +10 more
wiley +1 more source
NAD+-related dysregulation in asymptomatic phases of ALS: early biomarkers of the disease?
Background: nowadays, there is a lack of effective therapies for Amyotrophic Lateral Sclerosis (ALS). This is largely attributed to late diagnosis and incomplete understanding of the mechanisms determining the disease. Nicotinamide Adenine Dinucleotide
Sara Colombo +7 more
core +2 more sources
Insights into NAD homeostasis in the compartmentalized cell [PDF]
, 2015 The compartmentalized nature of eukaryotic cells requires the distribution of enzymes, metabolites, and cofactors among the organelles. This includes nicotinamide adenine dinucleotide (NAD), an essential coenzyme, precursor, and substrate to many ...
Van Linden, Magali R
core +1 more source
Creativity from Robert Sternberg's perspective [PDF]
Zbornik Radova Filozofskog Fakulteta u PrištiniThis paper aims to present and analyze both theories and models of Robert Sternberg, one of the most prolific and well-cited researchers in the field of creativity.
Nađ Ivona J.
doaj +1 more source