Results 271 to 280 of about 1,210,240 (343)

L-threonine Dehydrogenase From Escherichia Coli K-12 - Purification, Properties, And Role In L-threonine Catabolism.

, 1979
S A Boylan
openalex   +1 more source

A Patient‐Derived Organoid Biobank of Adamantinomatous Craniopharyngioma as a Platform for Drug Discovery

Advanced Science, EarlyView.
This study successfully establishes adamantinomatous craniopharyngioma (ACP) patient‐derived organoids (PDOs) that preserve the histopathological and genetic features of the original tumors. Through drug sensitivity assays and subsequent mechanistic analyses, the study demonstrates that Ceritinib exerts its inhibitory effects on ACP PDO growth by ...
Huarong Zhang, Chaohu Wang, Jun Fan, Zexin Chen, Haoying Yu, Yawen Bai, Tingcheng Zhang, Qianchao Zhu, Yiwen Feng, Peirong Niu, Jiaqian Chen, Liping Yang, Xueying Li, Lei Yu, Songtao Qi, Yi Liu   +15 more
wiley   +1 more source

Transcriptome Analysis and Its Application in Screening Genes Related to the Growth and Development of <i>Sarcomyxa edulis</i>. [PDF]

J Fungi (Basel)
Jiang W, Huang X, Wang P, Ahmad B, Yang T, Wang Z, Ren T, Xu J.   +7 more
europepmc   +1 more source

Structural enzymology studies with the substrate 3S‐hydroxybutanoyl‐CoA: bifunctional MFE1 is a less efficient dehydrogenase than monofunctional HAD [PDF]

Shruthi Sridhar, Tiila‐Riikka Kiema, Werner Schmitz, Mikael Widersten, Rik K. Wierenga   +4 more
openalex   +1 more source

T Cell Glycoengineering to Modulate Immune‐Tumor Crosstalk: A Universal Non‐Genetic Strategy for Enhanced Tumor Immunotherapy

Advanced Science, EarlyView.
This study describes a T cell surface engineering strategy that integrates polymer materials with tumor immunology, aiming to achieve broad‐spectrum anti‐tumor applications of glycopolymer‐engineered T (G‐T) cells via non‐genetic modification. Glycopolymer engineering generally modulates immune‐tumor crosstalk through specific cell‐cell interactions ...
Lihua Yao, He Yang, Fangjian Shan, Xiaomeng Niu, Yichen Wang, Hengyuan Zhang, Sujian Wang, Gaojian Chen, Hong Chen   +8 more
wiley   +1 more source

Mitochondrial Collapse Responsible for Chagasic and Post-Ischemic Heart Failure Is Reversed by Cell Therapy Under Different Transcriptomic Topologies. [PDF]

Curr Issues Mol Biol
Iacobas DA, Manzoor S, Daniels D, Iacobas S, Xi L.   +4 more
europepmc   +1 more source

Unraveling the tumor-promoting role of wildtype Isocitrate dehydrogenase 1 (IDH1) in human gliomas [PDF]

Xiang Li, Yiran Tao, Yuan Lyu, Junqi Li, Wulong Liang, Wanqing Liu, Nan Hu, Jing Zhou, Zian Li, 篠原 正徳, Lirui Dai, Yuqian Zheng, Zimin Shi, Weihua Hu, Shaolong Zhou, Qiao Shan, Xudong Fu, Xinjun Wang   +17 more
openalex   +1 more source

Onion‐Mitochondria Inhibit Lipopolysaccharide‐Induced Acute Lung Injury by Shaping Lung Macrophage Mitochondrial Function

Advanced Science, EarlyView.
Proposed model of orally administered onion mitochondria (O‐Mit) uptake by lung macrophages and fuse with macrophage mitochondria (M‐Mit). This fusion reprograms the metabolism of dysfunctional M‐Mit in lipopolysaccharide‐induced murine acute lung injury by modulating dynamin‐related protein 1 (DRP1) phosphorylation and cardiolipin peroxidation ...
Qingbo Xu, Yun Teng, Yinan Huang, Jingyao Mu, Lucy Teng, Hongjia Qian, Qiming Huang, Minmin Liu, Yi Zou, Lifeng Zhang, Michael L Merchant, Xiang Zhang, Jun Yan, Huang‐Ge Zhang   +13 more
wiley   +1 more source

An Alternative Metabolic Pathway of Glucose Oxidation Induced by Mitochondrial Complex I Inhibition: Serinogenesis and Folate Cycling. [PDF]

Int J Mol Sci
Abrosimov R, Borlepawar A, Hajieva P, Moosmann B.   +3 more
europepmc   +1 more source

X-Ray Diffraction Images For L-Threonine Dehydrogenase From Trypanosoma Brucei With Nad And Pyruvate Bound.

, 2016
Adjogatse Eyram, P.T. Erskine, Jon Cooper   +2 more
openalex   +1 more source