Results 281 to 290 of about 1,320,603 (414)

Unveiling the powerhouse: ASCL1-driven small cell lung cancer is characterized by higher numbers of mitochondria and enhanced oxidative phosphorylation. [PDF]

Cancer Metab
Solta A, Ernhofer B, Boettiger K, Lang C, Megyesfalvi Z, Mendrina T, Kirchhofer D, Timelthaler G, Szeitz B, Rezeli M, Aigner C, Haschemi A, Unger LW, Dome B, Schelch K.   +14 more
europepmc   +1 more source

STUDIES ON SUCCINIC DEHYDROGENASE

, 1956
Thomas P. Singer, Edna B. Kearney, Paul Bernath   +2 more
openalex   +1 more source

The enzymes of carbohydrate metabolism in Neurospora. 1. Succinic dehydrogenase [PDF]

, 1951
Charlie Shepherd
openalex   +1 more source

HNF3α Targets Nckap1l and Promotes Renal Fibrosis Following Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
Hepatocyte Nuclear Factor 3 alpha (HNF3α) is significantly upregulated in renal tubular epithelial cells of CKD patients and fibrotic mice. Deletion of HNF3α mitigates IRI‐induced renal fibrosis, while overexpression worsens it. HNF3α directly regulates NCK‐associated protein 1‐like (Nckap1l), whose overexpression exacerbates fibrosis.
Ling Hou, Yan Guo, Shuang Xu, Mi Bai, Weidong Cao, Yue Zhang, Zhanjun Jia, Aihua Zhang   +7 more
wiley   +1 more source

Isolation, Molecular, and Metabolic Profiling of Benzene-Remediating Bacteria Inhabiting the Tannery Industry Soil. [PDF]

Pol J Microbiol
Hussain N, Mohiuddin F, Muccee F, Bunny SM, Al Haddad AHI.   +4 more
europepmc   +1 more source

QUANTITATIVE ASSAY OF THE 3β-OL-DEHYDROGENASE SYSTEM IN WHOLE ADRENAL HOMOGENATE¹ [PDF]

, 1957
Benjamin Rubin, Ralph I. Dorfman
openalex   +1 more source

RFWD3 Reprograms Nucleotide Metabolism Through PHGDH to Induce Chemoresistance In Osteosarcoma

Advanced Science, EarlyView.
RFWD3 is identified as a key regulator of cisplatin (DDP) sensitivity in osteosarcoma using a genome‐wide CRISPR screen. RFWD3 promotes PHGDH ubiquitination, enhancing NAD+‐mediated nucleotide biosynthesis. Knocking out RFWD3 sensitized osteosarcoma cells to DDP.
Wenchao Zhang, Chi Yin, Lin Qi, Zhongyue Liu, Ruiling Xu, Chao Tu, Zhihong Li   +6 more
wiley   +1 more source

De-novo assembled mitochondrial genome of Bhadawari buffalo (Bubalus bubalis) reveals close divergence to Egyptian buffalo. [PDF]

BMC Vet Res
Santhosh A, Vohra V, Gandham RK, Alex R, Gowane G.   +4 more
europepmc   +1 more source

Human Placental Estradiol-17β Dehydrogenase

, 1958
Lorna J. Langer, Lewis L. Engel
openalex   +1 more source

CK2B Induces CD8+ T‐Cell Exhaustion through HDAC8‐Mediated Epigenetic Reprogramming to Limit the Efficacy of Anti‐PD‐1 Therapy in Non‐Small‐Cell Lung Cancer

Advanced Science, EarlyView.
αPD‐1 therapy has left an indelible mark in the field of NSCLC treatment; however, its efficacy is limited in clinical practice owing to the effector T‐cell exhaustion. These findings underscore CK2B as a promising target for overcoming the exhaustion of effector CD8+ T cells, thereby enhancing the efficacy of αPD‐1 and adoptive cell therapies in NSCLC.
Shaochuan Liu, Shiya Ma, Gen Liu, Lingjie Hou, Yong Guan, Liang Liu, Yuan Meng, Wenwen Yu, Ting Liu, Li Zhou, Zhiyong Yuan, Shuju Pang, Siyuan Zhang, Junyi Li, Xiubao Ren, Qian Sun   +15 more
wiley   +1 more source