Cerebral Inflammation in an Animal Ischemia–Reperfusion Model Comparing Histidine-Tryptophan-α-Ketoglutarate and Del Nido Cardioplegia [PDF]
LifeBrain injury and cerebral inflammation are frequent complications following cardiopulmonary bypass (CPB) resulting in neurocognitive dysfunction, encephalopathy, or stroke.
Kristin Klaeske +8 more
doaj +2 more sources
Vasculoprotective role of del Nido cardioplegia in open-heart surgery via modulation of E-Selectin, Endocan, and TNF-alpha coronary sinus blood samples [PDF]
Journal of Cardiothoracic SurgeryPurpose Cardioplegia is routinely used in cardiac surgery to prevent endothelial damage associated with ischemia-reperfusion. However, there is no consensus on the optimal vasculoprotective cardioplegia.
Fatih Kızılyel +7 more
doaj +2 more sources
Comparative analysis of del Nido cardioplegia versus blood cardioplegia in isolate coronary artery bypass grafting [PDF]
Journal of Cardiothoracic SurgeryBackground This study examined the efficacy of del Nido cardioplegia compared with traditional blood cardioplegia in adult cardiac surgery for isolated coronary artery bypass grafting by evaluating the early postoperative outcomes. Methods A total of 119
Soojin Lee +6 more
doaj +2 more sources
Modified Del Nido Cardioplegia with a 1:4 Crystalloid-to-Blood Ratio Versus Blood-Based St. Thomas Cardioplegia in Isolated Aortic Valve Replacement [PDF]
Journal of Cardiovascular Development and DiseaseThe aim of this study was to retrospectively compare modified Del Nido and blood-based St. Thomas cardioplegia in adult patients undergoing isolated aortic valve replacement (AVR).
Peter Jakub +7 more
doaj +2 more sources
Del Nido cardioplegia in adult cardiac surgery: A narrative review. [PDF]
PerfusionMyocardial protection during cardiac surgery is crucial for preventing ischemia-reperfusion injury and preserving myocardial function. Cardioplegia, a solution used to induce electromechanical cardiac arrest, is the fundamental method for myocardial protection during on-pump procedures.
Najmuddin II, Sainath P, Pillai VK.
europepmc +3 more sources
Del Nido cardioplegia versus cold blood cardioplegia in adult cardiac surgery: a meta-analysis of randomized clinical trials [PDF]
Journal of Cardiothoracic SurgeryObjective Systematic evaluation of the safety of del Nido cardioplegia compared to cold blood cardioplegia in adult cardiac surgery. Methods We systematically searched PubMed, EMbase, The Cochrane Library and ClinicalTrials.gov for randomized clinical ...
Congcong Li +8 more
doaj +2 more sources
The efficacy of modified bloodless del Nido cardioplegia in isolated aortic valve replacement. [PDF]
PLoS ONEThis study aimed to evaluate the safety and efficacy of a modified, bloodless Del Nido (DN) cardioplegia solution in patients undergoing isolated aortic valve replacement (AVR).
Bongyeon Sohn +3 more
doaj +2 more sources
Outcomes of coronary artery bypass surgery using modified del Nido cardioplegia in patients with poor ventricular function [PDF]
Journal of Cardiothoracic Surgery, 2023 Background del Nido cardioplegia (DN) has been shown to be safe in adult patients undergoing isolated coronary artery bypass grafting with normal left ventricular ejection fraction.
Samuel Brown +8 more
doaj +2 more sources
Traditional vs. modified Ringer lactate-based del Nido cardioplegia impacts on clinical outcomes in patients undergoing coronary artery bypass grafting: Results from a prospective, randomized, blinded trial [PDF]
The Journal of ExtraCorporeal TechnologyIntroduction: Myocardial protection with cardioplegia is a crucial approach to mitigate myocardial damage during coronary bypass grafting surgery (CABG) with cardiopulmonary bypass (CPB).
Kachoueian Naser +7 more
doaj +2 more sources
Comparison of routine del Nido cardioplegia vs two types of modified del Nido cardioplegias for myocardial protection among patients undergoing coronary artery bypass grafting (CABG) surgeries: A randomized double-blind clinical trial [PDF]
The Journal of ExtraCorporeal TechnologyBackground: The del Nido cardioplegia solution is a widely used method for myocardial protection in various settings. However, there is limited evidence of its effectiveness in adult cardiac surgery, and the baseline solution, Plasma Lyte A, is not ...
Ali Babar +8 more
doaj +2 more sources