Results 141 to 150 of about 50,977 (262)

Simultaneous Assessment of Skeletal Muscle Energetics and Blood Flow During Dynamic Exercise by Interleaved 31P‐MRS/1H‐MRI

open access: yesMagnetic Resonance in Medicine, Volume 96, Issue 1, Page 13-26, July 2026.
ABSTRACT Purpose To simultaneously measure skeletal muscle energetics and blood flow (BF) before, during, and after dynamic plantar flexion exercise (PFE). Methods Non‐localized pulse‐acquire phosphorus‐31 magnetic resonance spectroscopy (31P MRS) and phase contrast flow magnetic resonance imaging (1H MRI) using golden‐angle rotated spiral readouts ...
T. Jake Samuel   +6 more
wiley   +1 more source

MiR‐21‐5p Protects Embryonic Growth and Heart Function During Developmental Hypoxia by Dampening HIF Responses and Altering Gene Expression

open access: yesComprehensive Physiology, Volume 16, Issue 3, June 2026.
miR‐21‐5p protects embryonic growth and heart function during developmental hypoxia by dampening HIF responses and shifting gene networks toward improved cardiomyocyte survival and calcium handling. This work identifies miR‐21‐5p as a promising therapeutic target for preventing fetal growth restriction and cardiovascular impairment in high‐risk ...
Bernardo J. Krause   +12 more
wiley   +1 more source

A Study on the Characteristics of Sonazoid Contrast‐Enhanced Ultrasound in the Transitional Phase for Common Focal Liver Lesions and Its Value in Differential Diagnosis

open access: yesJournal of Ultrasound in Medicine, Volume 45, Issue 6, Page 1235-1245, June 2026.
Objective To investigate the value of transitional phase characteristics on Sonazoid contrast‐enhanced ultrasound (S‐CEUS) in the differential diagnosis of common focal liver lesions (FLLs). Materials and Methods This prospective multicenter study enrolled 122 participants with FLLs from 8 medical centers between December 2023 and March 2025. The study
Yunhao Luo   +10 more
wiley   +1 more source

Single‐Cell Sequencing Reveals That CCL2+ Adipose‐Derived Stem Cells Promote Diabetic Wound Healing Through the CCL2‐ACKR1 Signaling Axis

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
scRNA‐seq of human adipose and diabetic wounds revealed a CCL2+ ADSC subpopulation with high stemness and ECM‐enriched pathways. These cells serve as a signaling hub via TGFB1‐TGFBR1, IL34‐CSF1R, and CCL2‐ACKR1. Their exosomes (CCL2‐Exos), carrying CCL2, TGFB1, and IL34, accelerate diabetic wound healing in mice by promoting angiogenesis, collagen ...
Songyun Zhao   +10 more
wiley   +1 more source

Lithium Niobate Quadratic Integrated Nonlinear Photonics: Enabling Ultra‐Wide Bandwidth and Ultrafast Photonic Engines

open access: yesNanophotonics, Volume 15, Issue 9, 13 May 2026.
This perspective surveys emerging quantum and classical photonic applications across operating wavelengths and timescales, highlighting persistent technological gaps in integrated light sources. We examine the unique advantages of quadratic nonlinear photonics on the thin‐film lithium niobate (TFLN) platform and discuss strategies for realizing ...
Meng Tian   +7 more
wiley   +1 more source

Unraveling the Effect of Tramp Elements on Phase Transformations in Steels by Combining CALPHAD Modeling and Experiments

open access: yesAdvanced Engineering Materials, Volume 28, Issue 9, 6 May 2026.
This study investigates how tramp elements from increased scrap usage influence phase transformations in low‐alloyed steel. Combining dilatometry and microscopy reveal that tramp elements delay transformations, reduce critical cooling rates and increase hardenability.
Lukas Hatzenbichler   +5 more
wiley   +1 more source

A Comprehensive Review of Traditional and Machine Learning‐Assisted Diffuse Optical Spectroscopy and Imaging Techniques for Dermatological Applications

open access: yesAdvanced Photonics Research, Volume 7, Issue 5, May 2026.
This review critically examines clinical studies on both conventional and machine learning (ML)‐integrated diffuse optical spectroscopy and imaging methods for dermatological applications, with a primary focus on the past decade and inclusion of earlier foundational work where appropriate.
Iftak Hussain   +7 more
wiley   +1 more source

Nuclear Mechanotransduction Across the Metastatic Cascade: Decoding Spatiotemporal Heterogeneity in Cancer Dissemination

open access: yesAdvanced Science, Volume 13, Issue 25, 4 May 2026.
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song   +4 more
wiley   +1 more source

Robot‐Assisted Doppler Optical Coherence Tomography for Intraoperative Evaluation of Microvascular Anastomoses

open access: yesAdvanced Intelligent Systems, Volume 8, Issue 5, May 2026.
This work presents a robot‐assisted Doppler optical coherence tomography system for autonomous, wide‐field intraoperative assessment of microvascular anastomoses. Machine‐vision–guided probe positioning and adaptive scan planning enable three‐dimensional structural and hemodynamic imaging over extended vessel segments.
Xiaochen Li   +10 more
wiley   +1 more source

Marfan Syndrome Associated With Intellectual Disability and Behavioral Anomalies: Further Evidence for the Effect of Compound Heterozygous Variants in FBN1 on Phenotypic Severity

open access: yesAmerican Journal of Medical Genetics Part A, Volume 200, Issue 5, Page 1021-1035, May 2026.
ABSTRACT Marfan syndrome (MFS) is a rare connective tissue disorder characterized by involvement of the cardiovascular, ocular, and musculoskeletal systems. Pathogenic variants in FBN1 cause most of the MFS cases; however, intellectual disability (ID) is rarely observed. A non‐consanguineous Pakistani family with four affected individuals was recruited.
Azmatullah Khan   +4 more
wiley   +1 more source

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