Results 61 to 70 of about 4,173,115 (343)
MicroRNAs in Alzheimer's disease
Alzheimer's disease (AD) is a complex neurodegenerative disorder and is the most common form of dementia in the elderly. Accumulating evidence in AD research suggests that alterations in the microRNA (miRNA) network could contribute to risk for the ...
Charlotte Delay +2 more
doaj +1 more source
Boundary regularity of conformally compact Einstein metrics
We show that C^2 conformally compact Riemannian Einstein metrics have conformal compactifications that are smooth up to the boundary in dimension 3 and all even dimensions, and polyhomogeneous in odd dimensions greater than 3.Comment: Latex2e, 25 pages ...
Chrusciel, Piotr T. +3 more
core +5 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
This paper investigates an approach to substitution alternative to the implicit treatment of the $\lambda$-calculus and the explicit treatment of explicit substitution calculi. In this approach, substitutions are delayed (but not executed) explicitly.
openaire +2 more sources
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Task offloading under deterministic demand for vehicular edge computing
In vehicular edge computing (VEC) networks, the rapid expansion of intelligent transportation and the corresponding enormous numbers of tasks bring stringent requirements on timely task offloading.
Haotian Li, Xujie Li, Fei Shen
doaj +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
A delay analysis for opportunistic transmission in fading broadcast channels [PDF]
We consider a single-antenna broadcast block fading channel (downlink scheduling) with n users where the transmission is packet-based and all users are backlogged.
Hassibi, Babak, Sharif, Masoud
core
A Delay-Optimal Packet Scheduler for M2M Uplink
In this paper, we present a delay-optimal packet scheduler for processing the M2M uplink traffic at the M2M application server (AS). Due to the delay-heterogeneity in uplink traffic, we classify it broadly into delay-tolerant and delay-sensitive traffic.
Abdelhadi, Ahmed +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source

