Results 91 to 100 of about 46,797 (304)

Analytical approximation for logistic delay differential equation [PDF]

, 2020
Although the non-linear analytical techniques are fast developing, they still do not entirely satisfy mathematicians and engineers. Many researchers have conducted the study to find the analytical solution for the logistic delay differential equation ...
Maan, Normah, Barde, Aminu, Talib, Nurul Atiqah   +2 more
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Periodic Solutions in a Simple Delay Differential Equation

Mathematical and Computational Applications
A simple-form scalar differential equation with delay and nonlinear negative periodic feedback is considered. The existence of several types of slowly oscillating periodic solutions is shown with the same and double periods of the feedback coefficient ...
Anatoli Ivanov, Sergiy Shelyag
doaj   +1 more source

Stability of delay differential equations via delayed matrix sine and cosine of polynomial degrees

Advances in Difference Equations, 2017
In this paper, we study the finite time stability of delay differential equations via a delayed matrix cosine and sine of polynomial degrees. Firstly, we give two alternative formulas of the solutions for a delay linear differential equation.
Chengbin Liang, Wei Wei, JinRong Wang
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Dynamics of a state-dependent delay-differential equation

Electronic Journal of Qualitative Theory of Differential Equations
We present a detailed study of a scalar differential equation with threshold state-dependent delayed feedback. This equation arises as a simplification of a gene regulatory model.
Tomas Gedeon, Antony Humphries, Michael Mackey, Hans-Otto Walther, Zhao Wang   +4 more
doaj   +1 more source

Asymptotic Stability of Differential Equations with Infinite Delay

Journal of Applied Mathematics, 2012
A theorem on asymptotic stability is obtained for a differential equation with an infinite delay in a function space which is suitable for the numerical computation of the solution to the infinite delay equation.
D. Piriadarshani, T. Sengadir
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

Almost sure exponential stability of the Euler–Maruyama approximations for stochastic functional differential equations [PDF]

, 2011
By the continuous and discrete nonnegative semimartingale convergence theorems, this paper investigates conditions under which the Euler–Maruyama (EM) approximations of stochastic functional differential equations (SFDEs) can share the almost sure ...
Wu, Fuke, Peter E. Kloeden, Kloeden, Peter E., Mao, Xuerong, Fuke Wu, Xuerong Mao   +5 more
core   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source