Results 31 to 40 of about 321,539 (277)

Efficacy and Safety Analysis of Roxarestat in Regulating Renal Anemia in Patients on Maintenance Hemodialysis

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Objective To compare the efficacy and safety of roxarestat versus recombinant human erythropoietin (rhEPO) in the management of renal anemia in patients undergoing maintenance hemodialysis. Methods This was a prospective, open‐label, randomized controlled trial.
Lingling Chen, Junjie Zhu, Qiaonan Ge
wiley   +1 more source

Numerical Integration of a Class of Singularly Perturbed Delay Differential Equations with Small Shift

open access: yesInternational Journal of Differential Equations, 2012
We have presented a numerical integration method to solve a class of singularly perturbed delay differential equations with small shift. First, we have replaced the second-order singularly perturbed delay differential equation by an asymptotically ...
Gemechis File, Y. N. Reddy
doaj   +1 more source

On nonlinear delay differential equations [PDF]

open access: yesTransactions of the American Mathematical Society, 1994
We examine qualitative behaviour of delay differential equations of the form \[ y ′ ( t ) = h ( y ( t ) , y ( q t ) ) , y ( 0 ) = y 0
openaire   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Computational method for singularly perturbed delay differential equations with twin layers or oscillatory behaviour

open access: yesAin Shams Engineering Journal, 2015
In this paper, we have presented a computational method for solving singularly perturbed delay differential equations with twin layers or oscillatory behaviour. In this method, the original second order singularly perturbed delay differential equation is
D. Kumara Swamy   +3 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Linear Analysis of an Integro-Differential Delay Equation Model

open access: yesInternational Journal of Differential Equations, 2018
This paper presents a computational study of the stability of the steady state solutions of a biological model with negative feedback and time delay. The motivation behind the construction of our system comes from biological gene networks and the model ...
Anael Verdugo
doaj   +1 more source

Quintic B-Spline Technique for Numerical Treatment of Third Order Singular Perturbed Delay Differential Equation [PDF]

open access: yesInternational Journal of Mathematical, Engineering and Management Sciences, 2019
In this paper, a class of third order singularly perturbed delay differential equation with large delay is considered for numerical treatment. The considered equation has discontinuous convection-diffusion coefficient and source term.
Mandeep Kaur Vaid, Geeta Arora
doaj   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

On stability and boundedness of solutions of a certain fourth-order delay differential equation

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 1989
Using a Razumikhin - type theorem, we deduce sufficient conditions that guarantee the uniform asymptotic stability and boundedness of solutions of a scalar real fourth-order delay differential equation.
Emmanuel O. Okoronkwo
doaj   +1 more source

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