Results 111 to 120 of about 22,040 (222)

Scientific collaboration in data‐intensive research networks: PhD fellows' expectations and early experiences

open access: yesJournal of the Association for Information Science and Technology, EarlyView.
Abstract Collaboration has become important at all stages of research careers. In data‐intensive research fields such as wind energy, many PhD fellows are socialized to such collaboration in networks that train a cohort of PhD fellows. Based on interviews with 23 PhD fellows in four wind‐energy training networks, we investigate their expectations and ...
Grischa Fraumann   +3 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis   +5 more
wiley   +1 more source

Oseltamivir drug‐disease modelling in infants with influenza virus infection

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aims Oseltamivir is a commonly used neuraminidase inhibitor for treatment of influenza infection, but little data exist regarding concentration‐response relationships. Methods Pharmacokinetic (PK) and viral dynamic data from an earlier NIAID Collaborative Antiviral Study Group trial in paediatric patients with influenza from 0–23 months of age
Kun Wang   +4 more
wiley   +1 more source

Relationship between continuous infusion meropenem PK/PD target attainment and C‐reactive protein dynamics in onco‐haematologic patients with febrile neutropenia

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Meropenem is a second‐line antimicrobial agent in the treatment of febrile neutropenia in onco‐haematological patients. A population pharmacokinetic/pharmacodynamic (PK/PD) analysis for assessing the relationship between meropenem exposure and C‐reactive protein (C‐RP) over time was conducted.
Chun Liu   +7 more
wiley   +1 more source

Donanemab treatment effect by baseline tau burden and disease severity: Observations from the TRAILBLAZER-ALZ 2 trial. [PDF]

open access: yesAlzheimers Dement
Raket LL   +13 more
europepmc   +1 more source

Impact of parameter settings on the estimation of drug exposure with the individualized dispensing patterns method

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim To assess the impact of parameter settings when using the individualized dispensing patterns (IDP) method to estimate exposure duration from dispensing data. Methods We conducted a cohort study using a 2% representative sample of the French healthcare insurance database from 2013 to 2022.
Laëtitia Gosselin   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy