Results 141 to 150 of about 22,109 (264)

Does the Effect of Micronutrient Supplementation on Neonatal Survival Vary with Respect to the Percentiles of the Birth Weight Distribution?

, 2005
Scientific Background: In developing countries, higher infant mortality is partially caused by poor maternal and fetal nutrition. Clinical trials of micronutrient supplementation are aimed at reducing the risk of infant mortality by increasing birth ...
Zeger, Scott L., Dominici, Francesca, Katz, Joanne, Christian, Parul, Parmigiani, Giovanni   +4 more
core  

Scientific collaboration in data‐intensive research networks: PhD fellows' expectations and early experiences

Journal of the Association for Information Science and Technology, EarlyView.
Abstract Collaboration has become important at all stages of research careers. In data‐intensive research fields such as wind energy, many PhD fellows are socialized to such collaboration in networks that train a cohort of PhD fellows. Based on interviews with 23 PhD fellows in four wind‐energy training networks, we investigate their expectations and ...
Grischa Fraumann, Haakon Lund, Frans van der Sluis, Morten Hertzum   +3 more
wiley   +1 more source

Physical Fitness Profiles Among Children and Adolescents With ADHD and ASD: A Comparison With Typically Developing Peers

Autism Research, EarlyView.
ABSTRACT Children and adolescents with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) often present physical and motor challenges that may compromise health, yet direct comparisons between these neurodevelopmental conditions and typically developing (TD) peers remain limited.
Nerea Blanco‐Martínez, Rocío Carballo‐Afonso, Joel Estévez‐Agudo, Carlos Ayán‐Pérez, José Carlos Diz‐Gómez   +4 more
wiley   +1 more source

Psychological Impact of Autism Screening on Caregivers

Autism Research, EarlyView.
ABSTRACT Autism screening in childhood is common, yet little is known about its potential psychological impact on caregivers. The U.S. Preventive Services Task Force, an independent national panel of disease prevention experts, stated that this gap in knowledge limited their ability to endorse universal autism screening.
Ramkumar Aishworiya, Devon Gangi, Van Kim Ma, Chandni Parikh, Nor Azyati Yusoff, Narueporn Likhitweerawong, Sally Ozonoff   +6 more
wiley   +1 more source

Informational and Normative Influence on Conformity in Autism

Autism Research, EarlyView.
ABSTRACT This preregistered study examined whether adults with autism spectrum disorder (ASD) show reduced social conformity and whether any such reduction depends on the type of social influence. Social conformity—the tendency to adjust one's judgments to align with those of others—is typically driven by normative (acceptance‐seeking) and ...
Akiko Kobayashi, Takuya Makino, Yuka Mizuno, Hirotaka Kosaka, Keise Izuma   +4 more
wiley   +1 more source

Effect of developmental changes on pharmacokinetics of drugs used in the treatment of infant acute lymphoblastic leukaemia—A comprehensive review

British Journal of Clinical Pharmacology, EarlyView.
While the event‐free survival (EFS) of children treated for acute lymphoblastic leukaemia (ALL) has improved greatly in the last decades, the EFS for patients diagnosed with ALL before the age of one is still under 50%. This outcome further decreases when infants have a rearrangement in the gene encoding histone‐lysine N‐methyltransferase 2A (KMT2A ...
Tirsa de Kluis, Leiah J. Brigitha, Lidwien M. Hanff, Alwin D. R. Huitema, Inge M. van der Sluis, Meta H. M. Diekstra   +5 more
wiley   +1 more source

Estimating Reliability Indices and Confidence Intervals for Transit and Traffic at the Corridor Level

, 2017
As congestion worsens, the importance of rigorous methodologies to estimate travel-time reliability increases. Exploiting fine-granularity transit GPS data, this research proposes a novel method to estimate travel-time percentiles and confidence ...
Glick, Travis B
core  

Completion vs. early discontinuation of chemotherapy and the impact on 5‐year all‐cause mortality in women treated for early‐stage breast cancer from 2015 to 2020: A cohort study using a target trial emulation approach

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Chemotherapy is given for early‐stage breast cancer; however, some patients discontinue before completing all planned cycles. This study investigated the impact of early chemotherapy discontinuation on treatment outcomes. Methods This retrospective cohort study used a target trial emulation framework to conduct a causal analysis of the all‐
Luke Steventon, Chengsheng Ju, Kenneth K. C. Man, Rebecca Roylance, Diego Ottaviani, Chiara Creed, Michal Sladkowski, Alec Wisner, Li Wei, Pinkie Chambers   +9 more
wiley   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

Active surveillance of drug safety in healthcare data: Sequential monitoring of bacterial and serious urinary tract infection risk in sodium‐glucose cotransporter 2 inhibitor users

British Journal of Clinical Pharmacology, EarlyView.
Abstract Introduction Active surveillance of adverse events using healthcare data is emerging as complementary to the monitoring of spontaneous reports and stand‐alone pharmacoepidemiologic studies. The risk of urinary tract infections (UTIs) was listed as a special warning for sodium‐glucose cotransporter‐2 inhibitors (SGLT2is) when marketed in Europe
Haoxin Le, Dilsad Simay Peker, Lukas Frederic Westphal, Nikolai Brun, Christine Erikstrup Hallgreen, Morten Andersen   +5 more
wiley   +1 more source