Results 81 to 90 of about 61,103 (253)

Diminished Signal‐to‐Noise Ratio Disrupts Somatosensory Population Encoding and Drives Tactile Hyposensitivity in the Fmr1−/y Autism Model

Advanced Science, EarlyView.
This study provides a translational approach for linking neural activity to tactile deficits in autism. By combining psychophysics with cortical recordings in a mouse model of autism, we show that low signal‐to‐noise ratio in somatosensory neurons weakens population encoding of fine touch, impairing detection, decoding, and leading to perceptual ...
Ourania Semelidou, Théo Gauvrit, Célien Vandromme, Alexandre Cornier, Anna Saint‐Jean, Yves Le Feuvre, Melanie Ginger, Andreas Frick   +7 more
wiley   +1 more source

Phenotypic Diversity and Outcomes in Pediatric NMDA Receptor Encephalitis: A 15‐Year Retrospective Study from the Largest Children's Hospital in the United States

Advanced Science, EarlyView.
ABSTRACT Anti‐NMDAR encephalitis (NMDARE) is an autoantibody‐mediated disorder characterized by seizures, movement disorders, neurocognitive deficits, and psychosis, but the complete phenotypic heterogeneity, and outcomes are incompletely understood in children.
Alexander J. Sandweiss, Timothy Erickson, Yike Jiang, Varun Kannan, Jonathan M. Yarimi, Kristen S. Fisher, Nikita Shukla, Tim Lotze, Eyal Muscal, Kristy O. Murray   +9 more
wiley   +1 more source

ALGORITHM FOR MONITORING PHYSICAL AND PUBERTAL DEVELOPMENT IN CHILDREN WITH CHRONIC DISEASES

Buletinul Academiei de Ştiinţe a Moldovei: Ştiinţe Medicale
Children with chronic diseases frequently present growth disorders and delayed puberty, complications that negatively impact general health status and quality of life.
Rodica EREMCIUC, Ninel REVENCO
doaj   +1 more source

Mild Focal Cooling Decouples Dendrites to Reconfigure Cortical Output

Advanced Science, EarlyView.
Mild cooling of the cortical surface selectively modulates apical dendritic excitability, plasticity, and somato‐dendritic coupling, while uncoupling these effects from basal dendrites, and reshapes apical‐driven responses in barrel cortex during whisker touch.
Meisam Habibi Matin, Shulan Xiao, Krishna Jayant   +2 more
wiley   +1 more source

What 'outliers' tell us about missed opportunities for tuberculosis control: a cross-sectional study of patients in Mumbai, India

BMC Public Health, 2010
Background India's Revised National Tuberculosis Control Programme (RNTCP) is deemed highly successful in terms of detection and cure rates. However, some patients experience delays in accessing diagnosis and treatment.
Porter John DH, Bamne Arun, Gupte Himanshu, Kielmann Karina, Pradhan Anagha, Rangan Sheela   +5 more
doaj   +1 more source

Measuring the delay time distribution of binary neutron stars. II. Using the redshift distribution from third-generation gravitational wave detectors network

, 2019
We investigate the ability of current and third-generation gravitational wave (GW) detectors to determine the delay time distribution (DTD) of binary neutron stars (BNS) through a direct measurement of the BNS merger rate as a function of redshift.
Berger, Edo, Chen, Hsin-Yu, Ng, Ken K. -Y., Safarzadeh, Mohammadtaher, Scannapieco, Evan, Vitale, Salvatore, Whittle, Chris   +6 more
core   +1 more source

An Implanted Tooth That Can Feel

Advanced Science, EarlyView.
To endow the implanted tooth with masticatory perception, herein we demonstrate that a 3D‐printed piezoelectric‐core/robust‐sheath implanted tooth can rebuild the sensing feedback, serving as “mechanoreceptors” in converting the mechanical chewing force to electrical signals, and up to brain through surrounding alveolar nerve system.
Yaru Cao, Zhenhua Wu, Jiwei Sun, Ke Song, Jiayi Li, Yujin Li, Wenqi Chen, Hanyu Li, Shue Li, Cheng Yang, Silin Liu, Yunyun Han, Bin Su, Yumei Ding   +13 more
wiley   +1 more source

Heatwaves and dengue outbreaks in Hanoi, Vietnam: New evidence on early warning.

PLoS Neglected Tropical Diseases, 2020
BACKGROUND:Many studies have shown associations between rising temperatures, El Niño events and dengue incidence, but the effect of sustained periods of extreme high temperatures (i.e., heatwaves) on dengue outbreaks has not yet been investigated.
Jian Cheng, Hilary Bambrick, Laith Yakob, Gregor Devine, Francesca D Frentiu, Do Thi Thanh Toan, Pham Quang Thai, Zhiwei Xu, Wenbiao Hu   +8 more
doaj   +1 more source

Insulin signal transduction mediates ethanol-induced feeding dysfunction in a fly model of Fetal Alcohol Spectrum Disorder [PDF]

, 2019
Fetal alcohol spectrum disorder (FASD) is the leading cause of congenital intellectual disabilities in the Western World, with a worldwide prevalence of 2-11% of all births.
Matsubara, Manae
core   +1 more source

Natural Variation of NAR5 Determines Nitrogenase Activity and the Yield in Soybean

Advanced Science, EarlyView.
This study identified NAR5, a gene encoding a subtilisin‐like protease, that regulates nitrogenase activity in soybean nodules. Overexpressing NAR5 delayed nodule senescence, enhancing nitrogenase activity, yield, and low‐nitrogen tolerance. The elite haplotype NAR5HapI‐1 linked to superior nitrogenase activity and greater seed weight has been ...
Chao Ma, Hanyu Zhao, Haojie Feng, Xulun Dong, Lin Chen, Mingliang Yang, Runyi Chen, Chengjun Lei, Chunyan Liu, Qingshan Chen, Dawei Xin, Jinhui Wang   +11 more
wiley   +1 more source