Results 31 to 40 of about 6,134 (254)
Molecular Oncology, EarlyView.Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary +1 more
wiley +1 more source
DRANS: Daily Routine Analysis for Node Searching in delay tolerant networks
International Journal of Distributed Sensor Networks, 2017 In delay tolerant networks, the success rate and the transmission speed are restricted by limited social interaction and complex node mobility pattern analysis. To increase the success rate and reduce the transmission delay in delay tolerant networks, we
Xingyu He, Guisong Yang, Hao Zhang
doaj +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
Routing Protocols for Vehicular Delay Tolerant Networks: A Survey
International Journal of Distributed Sensor Networks, 2015 Recently, the delay tolerant networks (DTN) have been utilized in various operational communication paradigms. This includes the communication scenarios that are subject to disruption and disconnection as well as the scenarios with high delay and ...
Hyunwoo Kang +3 more
doaj +1 more source
Cryptographic Key Management in Delay Tolerant Networks: A Survey
Future Internet, 2017 Since their appearance at the dawn of the second millennium, Delay or Disruption Tolerant Networks (DTNs) have gradually evolved, spurring the development of a variety of methods and protocols for making them more secure and resilient.
Sofia Anna Menesidou +2 more
doaj +1 more source
Mutant NPM1 in Acute Myeloid Leukemia Initiation and Maintenance
Aging and Cancer, EarlyView.NPM1 mutations drive acute myeloid leukemia by acting as neomorphic transcriptional regulators that cooperate with Menin–MLL and XPO1 to sustain HOX/MEIS1 expression and block differentiation. Targeting these mutant‐specific transcriptional dependencies provides a rational therapeutic strategy for NPM1‐mutated AML.
Yanan Jiang +3 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Super‐Refractory Status Epilepticus (SRSE) is a rare, life‐threatening neurological emergency with unclear etiology in many cases. Mitochondrial dysfunction, often due to disease‐causing genetic variants, is increasingly recognized as a cause, with each gene producing distinct pathophysiological mechanisms.
Pouria Mohammadi +2 more
wiley +1 more source
Social network-based trustworthy routing in delay tolerant networks
Tongxin xuebao, 2010 A trustworthy routing protocol was proposed based on social networks for delay tolerant networks（DTN）,which ensured the messages to be sent to the destination node efficiently and reliably against more selfness nodes.With a method of relation evaluation ...
YU Hai-zheng1, MA Jian-feng1, BIAN Hong3
doaj +2 more sources
Routing on Delay Tolerant Sensor Networks [PDF]
, 2009 Delay (or disruption) tolerant sensor networks may be modeled as Markovian evolving graphs [1]. We present experimental evidence showing that considering multiple (possibly not shortest) paths instead of one fixed (greedy) path can decrease the expected time to deliver a packet on such a network by as much as 65 per cent depending on the probability ...
Michael Keane +3 more
openaire +1 more source
Challenges in deploying a delay tolerant network [PDF]
Proceedings of the third ACM workshop on Challenged networks, 2008 Delay Tolerant Networking (DTN) is the area of networking that addresses challenges in disconnected, disrupted, and networks without end-to-end connection. DTN has been an active area of research in the recent past, there have been attempts to use concepts from DTN to extend the reach of networks to remote rural areas as well.
Shrikant Naidu +3 more
openaire +1 more source