Results 211 to 220 of about 2,044,874 (243)
Bioactive constituents, mechanisms of action, and potential applications of Lonicerae Japonicae Flos as a dietary natural product for promoting gut health and managing ulcerative colitis and colorectal cancer. ABSTRACT Lonicerae Japonicae Flos (LJF), a traditional Chinese herb with applications in both medicine and nutrition, has emerged as a promising
Xiaoyu Huang +5 more
wiley +1 more source
ABSTRACT Background and Aims Knee osteoarthritis (KOA) is a leading cause of functional impairment and decreased quality of life. Exercise is the recommended approach; however, adjunct interventions such as kinesio taping (KT) have gained attention for potential to reduce pain, improve proprioception, and enhance functional performance.
Md. Zahid Hasan +6 more
wiley +1 more source
Natural Product‐Derived Vesicles in Nanotherapeutics
Natural product‐derived vesicles (NPVs) are an emerging nature‐based nanotherapeutic that can deliver bioactive metabolites into the target site and induce beneficial mechanisms. A practical, chronological bench‐to‐bedside approach throughout the entire NPV development process is expected to resolve challenges encountered in NPV studies.
Kartiko Arif Purnomo, Tsong‐Long Hwang
wiley +1 more source
Passive ASO association with NSC‐EVs enhances neuronal uptake and CNS accumulation. NSC‐EV‐ASOs suppress pathogenic targets in ALS cellular models and, following intranasal administration, delay disease onset and improve motor function in SOD1‐G93A mice. These findings provide proof‐of‐concept evidence supporting NSC‐EVs as a platform for enhancing CNS
Yaochao Zheng +8 more
wiley +1 more source
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley +1 more source
Somatic and gastrointestinal symptoms longitudinally predict early adolescent disordered eating
Abstract Objectives Somatic complaints have been identified as potential risk factors for the development of disordered eating. Emerging evidence suggests that gastrointestinal (GI) symptoms, specifically, may precede and contribute to disordered eating onset. However, existing research in early adolescents is limited and largely cross‐sectional.
Antonia L. Hamilton +2 more
wiley +1 more source
From preclinical promise to clinical translation in intervertebral disc degeneration (IDD). Robust preclinical evidence supports a range of biologic therapies, with consistent improvements in imaging, extracellular matrix composition, inflammation, and behavior.
Luca Ambrosio +5 more
wiley +1 more source
Pain quality patterns in delayed onset muscle soreness of the lower back suggest sensitization of fascia rather than muscle afferents: a secondary analysis study. [PDF]
Brandl A +5 more
europepmc +1 more source
Migraine: Epidemiology, Risk Factors, Pathophysiology, and Treatment
Migraine is a highly prevalent, female‐predominant, and disabling brain disorder shaped by genetic susceptibility, hormonal influences, modifiable attack factors, and comorbidity‐related progression. This review integrates current evidence on migraine epidemiology, phase‐specific neurovascular and neuroglial mechanisms, including CGRP signaling and ...
Weiwei Lu +9 more
wiley +1 more source

