Results 91 to 100 of about 56,788 (302)
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Digital technologies hold promise for transforming healthcare by enhancing personalized treatments and offer valuable opportunities to improve patient care. Here, we evaluated several novel, self‐administered, home‐based, digital endpoints for their association with corresponding conventional standard clinical measures (primary) in ...
Arne Mueller +14 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Variants in SLC6A1, encoding the GABA transporter 1 (GAT‐1), cause epilepsy, autism spectrum disorder, and developmental delay via loss of GABA uptake, impaired trafficking, and ER retention. We previously found that 4‐Phenylbutyrate (PBA), an FDA‐approved drug, restores GABA uptake and reduces seizures in SLC6A1‐related disorders ...
Melissa B. DeLeeuw +5 more
wiley +1 more source
Onasemnogene Abeparvovec in Patients With SMA: Interim Results of the RESTORE Registry in Japan
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective There are limited real‐world data regarding the safety and effectiveness of onasemnogene abeparvovec (OA; Zolgensma) infusion, a one‐time gene replacement therapy, for Japanese patients with spinal muscular atrophy (SMA). We aimed to improve understanding of the real‐world outcomes for OA in Japan.
Kayoko Saito +8 more
wiley +1 more source
, 2015 This paper considers the stability problem of multiple equilibria for delayed neural networks with discontinuous activation functions. By virtue of the fixed point theorem, it is found that under some sufficient conditions, n neurons delayed neural ...
Nie, Xiaobing (R18222) +1 more
core +1 more source
Synchronization between Bidirectional Coupled Nonautonomous Delayed Cohen-Grossberg Neural Networks
Abstract and Applied Analysis, 2012 Based on using suitable Lyapunov function and the properties of M-matrix, sufficient conditions for complete synchronization of bidirectional coupled nonautonomous Cohen-Grossberg neural networks are obtained.
Qiming Liu, Rui Xu
doaj +1 more source
Global Mittag-Leffler synchronization of delayed fractional-order memristive neural networks
Advances in Difference Equations, 2018 This paper deals with the global Mittag-Leffler synchronization of fractional-order memristive neural networks (FMNNs) with time delay. Since the FMNNs are essentially a class of switched systems with irregular switching laws, it is more difficult to ...
Yingjie Fan +4 more
doaj +1 more source
White Matter Microstructural Abnormalities in Neonatal Onset Genetic Epilepsy
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective Recent evidence indicates that epilepsy is associated with abnormal white matter. If seizures alter white matter, then the impact upon network function, epileptogenesis, and cognition could be pronounced in neonates undergoing rapid developmental myelination. Neonates with epilepsy due to nonstructural genetic causes provide a unique
Amanda G. Sandoval Karamian +8 more
wiley +1 more source
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To evaluate the expression of nine blood RNA biomarkers in a clinical trial based on genes previously identified in an experimental monkey model of stroke for diagnosis feasibility and prognostication. Methods IBIS‐CT1 was a prospective longitudinal study enrolling patients with ischemic stroke (IS) or intracerebral hemorrhage (ICH ...
Salomé Retailleau +11 more
wiley +1 more source
Global Robust Stability of Interval Delayed Neural Networks: Modified Approach
, 2009 A criterion for the global robust stability of Hopfield-type delayed neural networks with the intervalized network parameters is presented. The criterion, which is derived by utilizing the idea of splitting the given interval into two intervals, is in ...
Sıngh, Vımal, Singh, Vimal
core +1 more source
A Q‐Learning Algorithm to Solve the Two‐Player Zero‐Sum Game Problem for Nonlinear Systems
International Journal of Adaptive Control and Signal Processing, Volume 39, Issue 3, Page 566-581, March 2025.A Q‐learning algorithm to solve the two‐player zero‐sum game problem for nonlinear systems. ABSTRACT This paper deals with the two‐player zero‐sum game problem, which is a bounded L2$$ {L}_2 $$‐gain robust control problem. Finding an analytical solution to the complex Hamilton‐Jacobi‐Issacs (HJI) equation is a challenging task.
Afreen Islam +2 more
wiley +1 more source