Results 111 to 120 of about 584,122 (264)

Monitoring rodents' life history by body temperature and activity

open access: yesWildlife Biology, EarlyView.
European hamster populations are rapidly declining all over their distribution area. One of the suggested reasons is a strong and ongoing decrease in the reproductive output of about 77% since the nineteen twenties. The cause of this decline is, however, unknown.
S. Monecke   +9 more
wiley   +1 more source

Advent of NK3R Antagonists for the Treatment of Menopausal Hot Flushes: A Narrative Review

open access: yesBJOG: An International Journal of Obstetrics &Gynaecology, EarlyView.
ABSTRACT The menopause transition is marked by symptoms predominantly attributed to declining oestrogen levels. Approximately 80% of women experience associated symptoms, and 25% experience severe symptoms. The commonest are vasomotor symptoms (VMS), collectively referring to hot flushes and/or night sweats.
Aaran H. Patel   +5 more
wiley   +1 more source

Reproductive Biology, Mating System, and Extended Natal Association in the Echolocating Dalou Mountains Tree Mouse (Typhlomys daloushanensis): Insights Into Sensory Adaptation and Life‐History Strategy

open access: yesIntegrative Zoology, EarlyView.
Typhlomys daloushanensis, a poorly known and unique echolocating rodent. Using a captive breeding colony, we quantify key reproductive parameters, including gestation length, litter size, interbirth interval, and development to maturity, and evaluate these in relation to mating system structure.
Juncheng Li   +8 more
wiley   +1 more source

Estimating thresholds for risk of cannabis use disorder using standard delta‐9‐tetrahydrocannabinol (THC) units

open access: yesAddiction, EarlyView.
Abstract Background and aims Lower risk guidelines for safer levels of cannabis use could help to reduce the health burden posed by cannabis use disorder (CUD). We aimed to estimate risk thresholds for CUD based on delta‐9‐tetrahydrocannabinol (THC) consumption using standard THC units (1 unit = 5 mg THC).
Rachel Lees Thorne   +9 more
wiley   +1 more source

Postcode‐Level Variation and Environmental Determinants of Respiratory Allergies in a Large German Cohort

open access: yesAllergy, EarlyView.
Young children (0–9 years) and residents of urban areas appeared particularly vulnerable to respiratory allergy development and exacerbation. Incidence showed nonlinear associations with PM10, PM2.5, temperature, and alder/birch pollen, while DPMR showed similar patterns, except for NO2 and the interaction O3*NO2.
Trang Dao‐Siebel   +6 more
wiley   +1 more source

Mesenchymal Stem Cells From a Klinefelter Syndrome Patient: Functional Characterization and Therapeutic Implications

open access: yesAndrology, EarlyView.
ABSTRACT Background Cell therapy, particularly those utilizing mesenchymal stem/stromal cells (MSCs), is gaining traction as a therapeutic option for regenerative treatment in patients with limited therapeutic options. Although the safety of MSC‐based interventions is well established, uncertainties remain regarding how genetic abnormalities and ...
Marzena Zychowicz   +12 more
wiley   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

open access: yesAndrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Sleep Disorders in Klinefelter Syndrome and Other Sex Chromosome Aneuploidies: A Narrative Review

open access: yesAndrology, EarlyView.
ABSTRACT Background Sex chromosome aneuploidies (SCAs) are among the most frequent types of chromosomal aneuploidies and include Klinefelter syndrome (47,XXY and higher‐grade variants), 47,XYY syndrome, Turner syndrome (45,X), and trisomy X (47,XXX).
Roberto Paparella   +3 more
wiley   +1 more source

Incidence of Delayed Puberty in Adolescents : A Population-Based Study in a County in Central Sweden

open access: yes, 2018
Introduction: Delayed puberty is defined as the absence of physical signs of puberty by the age of 14 years in boys and 13 years in girls. According to this definition, the prevalence of delayed puberty would be 2%, if the ages of pubertal onset were ...
Rodanaki, Maria,   +2 more
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