Results 221 to 230 of about 72,472 (321)

mTOR blockade prevents progressive proteinuria but induces hyperglycaemia in obese Dahl salt‐sensitive rats before puberty

Experimental Physiology, EarlyView.
Abstract Previous studies have demonstrated that mammalian target of rapamycin (mTOR) activity is significantly increased in the kidneys of Dahl salt‐sensitive (SS) rats during the development of renal injury. Therefore, in the present study we examined whether blockade of mTOR with rapamycin inhibits renal injury in Dahl salt‐sensitive leptin receptor
Sautan Mandal, Andrea K. Brown, Ubong S. Ekperikpe, Anukool A. Bhopatkar, Krystle M. Hughes, Tyler D. Johnson, Jonita S. Cooper, Konnor T. Wilbert, Denise C. Cornelius, Jan M. Williams   +9 more
wiley   +1 more source

A Shared Genetic Basis for Self-Limited Delayed Puberty and Idiopathic Hypogonadotropic Hypogonadism [PDF]

, 2015
Jia Zhu, Ruth Choa, Michael H. Guo, Lacey Plummer, Cassandra Buck, Mark R. Palmert, Joel N. Hirschhorn, Stephanie B. Seminara, Yee-Ming Chan   +8 more
openalex   +1 more source

Evaluation of metabolism‐related molecules in rat model of autism spectrum disorders

Experimental Physiology, EarlyView.
Abstract Autism spectrum disorders (ASD) are neurodevelopmental pathologies. Investigating both sexes is crucial for understanding sex‐specific manifestations of ASD. This study aims to examine ASD‐like behaviours and metabolic alterations in male and female rats prenatally exposed to valproic acid (VPA).
Süeda Tunçak, Ayşen Çakır, Bülent Gören, Nevzat Kahveci   +3 more
wiley   +1 more source

Learning problems, delayed development, and puberty

, 2004
Beverly A. Wright, Steven G. Zecker
openalex   +1 more source

Growth Standards for Children With Smith–Magenis Syndrome (SMS)

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 569-578, March 2026.
ABSTRACT Smith–Magenis syndrome (SMS, OMIM 182290) is a complex syndromic diagnosis marked by neurobehavioral differences and distinct facial dysmorphisms, caused by haploinsufficiency of the retinoic acid‐1 (RAI1) gene either by a pathogenic sequence variant or deletion at chromosome 17p11.2 involving a portion or all of this gene.
Julie Hoover‐Fong, John McGready, Leah Fleming, Kerry Schulze, Folami Duncan, Alexis Leonard, Marie Christine de Blois Boucard, Danilo Moretti‐Ferreira, Andrea L. Gropman, Wendy J. Introne, Ann C. M. Smith   +10 more
wiley   +1 more source

Outcomes and experiences of adults with congenital hypogonadism can inform improvements in the management of delayed puberty. [PDF]

J Pediatr Endocrinol Metab
Howard SR, Quinton R.
europepmc   +1 more source

PRACTICE VARIATION IN THE MANAGEMENT OF GIRLS AND BOYS WITH DELAYED PUBERTY. [PDF]

Endocr Pract, 2020
Zhu J, Feldman HA, Eugster EA, Fechner PY, Nahata L, Thornton PS, Chan YM.   +6 more
europepmc   +1 more source

Alcohol Delays the Onset of Puberty in the Female Rat by Altering Key Hypothalamic Events

, 2018
Vinod K. Srivastava, Jill K. Hiney, W. Les Dees   +2 more
openalex   +2 more sources

Spuriously Elevated Serum IGF-1 in Adult Individuals with Delayed Puberty: A Diagnostic Pitfall [PDF]

, 2010
Syed Ali Imran, Michael Pelkey, David B. Clarke, Dale H. Clayton, Peter Trainer, Shereen Ezzat   +5 more
openalex   +1 more source

A Systematic Review and Meta‐Analysis of the Birth Prevalence of Turner Syndrome

American Journal of Medical Genetics Part A, Volume 200, Issue 3, Page 579-591, March 2026.
ABSTRACT Turner syndrome, a chromosomal disorder, causes short stature, pubertal arrest, amenorrhea, and infertility in females. Prevalence estimates vary widely; however, reliable estimates are important for public health initiatives. Therefore, a meta‐analysis was undertaken.
David Hinds, Jeanne M. Pimenta, Andrea Low, Deepali Mittal, Smeet Gala, Digant Gupta   +5 more
wiley   +1 more source