Results 81 to 90 of about 163,521 (283)
Kinetochore inactivation by expression of a repressive mRNA. [PDF]
, 2017 Differentiation programs such as meiosis depend on extensive gene regulation to mediate cellular morphogenesis. Meiosis requires transient removal of the outer kinetochore, the complex that connects microtubules to chromosomes.
Chen, Jingxun +8 more
core +2 more sources
Advanced Science, EarlyView.This study shows that BLADE‐ON‐PETIOLE (BOP) proteins regulate floral abscission and senescence in tomato by interacting with TFAM1 to form transcriptional condensates controlling the ARABIDOPSIS THALIANA HOMEOBOX GENE 1 (ATH1)‐mediated abscission pathway.
Nan Xiao +7 more
wiley +1 more source
Diverse Sequences within Tlr Elements Target Programmed DNA Elimination in \u3cem\u3eTetrahymena Thermophila\u3c/em\u3e [PDF]
, 2003 Tlr elements are a novel family of ~30 putative mobile genetic elements that are confined to the germ line micronuclear genome in Tetrahymena thermophila.
Karrer, Kathleen M. +1 more
core +1 more source
Genetic Requirements for Intra-Chromosomal Deletions [PDF]
, 2020 Chromosomal deletions are one of the most dangerous types of DNA damage and often arise as a result of inappropriately repaired DNA double strand breaks (DSB).
McPherson, Matthew
core
Analysis of phosphatases in ER-negative breast cancers identifies DUSP4 as a critical regulator of growth and invasion. [PDF]
, 2016 Estrogen receptor (ER)-negative cancers have a poor prognosis, and few targeted therapies are available for their treatment. Our previous analyses have identified potential kinase targets critical for the growth of ER-negative, progesterone receptor (PR)-
Brown, Powel H +13 more
core +2 more sources
Advanced Science, EarlyView.Integration of a pancreatic eQTL map with a GWAS meta‐analysis identifies 82 putative functional variants and 15 genes. The association between rs11102484 and pancreatic cancer risk is observed in a total of 5699 cases and 8467 controls. The G allele of rs11102484 weakens ZNF263 binding and the silencer‐promoter interaction, thereby increasing ST7L ...
Xiaoyang Wang +14 more
wiley +1 more source
Heteroduplex analysis of tra delta f' plasmids and the mechanism of their formation [PDF]
, 1977 Four tra delta FargG+ plasmids, derived from matings between Hfr AB312 and a recA recipient, have been shown to have deletions of at least 50% of the F genome, including the region in which the tra genes map.
Clark, Alvin J. +2 more
core +1 more source
Gene expression programming approach to event selection in high energy physics [PDF]
, 2006 Gene Expression Programming is a new evolutionary algorithm that overcomes many limitations of the more established Genetic Algorithms and Genetic Programming. Its first application to high energy physics data analysis is presented.
Teodorescu, L
core +1 more source
Advanced Science, EarlyView.ABSTRACT Gut microbiota dysbiosis promotes colorectal cancer (CRC) tumorigenesis. A global fecal metagenomic analysis identified Gemella morbillorum as a key contributor to the CRC‐associated microbiota. Fluorescence in situ hybridization revealed that Gemella morbillorum is enriched in CRC tumor tissues compared to adjacent normal tissues.
Zhen Wang +8 more
wiley +1 more source
Advanced Science, EarlyView.Integrated multi‐omic profiling maps the gene‐regulatory landscape of the coelomic mesothelium across heart, lung, and pancreas. A cardiac‐restricted regulatory program is uncovered in which TBX20 activates heart mesothelial (epicardial) cis‐regulatory elements, while MAF emerges as a conserved regulator of mesothelial identity.
Quang Minh Dang +3 more
wiley +1 more source