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Retinoblastoma is a rare cancer of the infant retina that is diagnosed in approximately 8,000 children each year worldwide. It forms when both retinoblastoma gene (RB1) alleles are mutated in a susceptible retinal cell, probably a cone photoreceptor precursor.
Darren Orbach +2 more
exaly +9 more sources
From 7% to 10% of all retinoblastomas and from 44% to 71% of familial retinoblastomas in developed countries are diagnosed in the neonatal period, usually through pre- or post-natal screening prompted by a positive family history and sometimes ...
Tero T Kivelä, Theodora Hadjistilianou
doaj +6 more sources
Recent Developments in Retinoblastoma
Retinoblastoma represents 3% of all childhood cancers, and is the most common intraocular malignancy of childhood. It is fatal if untreated. The management of retinoblastoma has gradually evolved over the past few decades, with an aim to not only ...
Raksha Rao, Santosh G Honavar
doaj +3 more sources
Management of Retinoblastoma [PDF]
A B, Reese, R M, Ellsworth
exaly +4 more sources
Objective To explore living with heritable retinoblastoma, specifically survivors’ perceived role of regular follow-up at a retinoblastoma survivorship clinic.Methods and analysis Adult survivors of heritable retinoblastoma were recruited from the ...
Stina Lou +7 more
doaj +1 more source
Retinoblastoma is a radiosensitive malignancy of neuroblastic origin that primarily affects young children. Its relatively low incidence belies its potential importance in the understanding of tumor biology in general. A case is made for referral of all retinoblastoma patients to centers with retinoblastoma protocols.
Marchevsky, Silvia +4 more
openaire +5 more sources
Incidence and geographic distribution of retinoblastoma in Ethiopia
Introduction Retinoblastoma is the most frequent intraocular malignancy of the eye in children, occurring in early childhood. Based on global estimates, Ethiopia is expected to observe over 200 new retinoblastoma cases per year, however without a cancer ...
Sadik Taju Sherief +7 more
doaj +1 more source
Sclero-conjunctival ischaemia secondary to intra-arterial chemotherapy for retinoblastoma
Purpose: Intra-arterial chemotherapy (IAC), delivered directly to the globe via the internal carotid artery is now an established treatment for retinoblastoma.
Lisa McAnena +5 more
doaj +1 more source

